About lab
One published Lab
Build with this Lab. Run it anywhere.
Use the same immutable release locally or through managed cloud execution, with its exact version and provenance preserved.
Preparing exact examples…
Source-faithful physiology lab for Gonzalezheydrich, Steingard, Kohane, 1994. Public controls and outputs are mapped to real source symbols for source-model physiology.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_corticotropin_releasing_hormone",
"label": "Initial Corticotropin Releasing Hormone",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.initial_corticotropin_releasing_hormone",
"description": "Initial value for Corticotropin Releasing Hormone. Maps to source symbol `CRH`. Units: mcg_ml. Naming evidence: source metadata names `CRH` as `corticotropin releasing hormone`.",
"accepted_units": [
"mcg_ml"
]
},
{
"name": "initial_acetylcholine",
"label": "Initial Acetylcholine",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.initial_acetylcholine",
"description": "Initial value for Acetylcholine. Maps to source symbol `ACTH`. Units: mcg_ml. Naming evidence: source metadata names `ACTH` as `acetylcholine`.",
"accepted_units": [
"mcg_ml"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.variable_labels"
},
{
"name": "corticotropin_releasing_hormone",
"label": "Corticotropin Releasing Hormone",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.corticotropin_releasing_hormone",
"description": "Corticotropin Releasing Hormone. Maps to source symbol `CRH`. Units: mcg_ml. Naming evidence: source metadata names `CRH` as `corticotropin releasing hormone`."
},
{
"name": "acetylcholine",
"label": "Acetylcholine",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.acetylcholine",
"description": "Acetylcholine. Maps to source symbol `ACTH`. Units: mcg_ml. Naming evidence: source metadata names `ACTH` as `acetylcholine`."
},
{
"name": "cortisol",
"label": "Cortisol",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.cortisol",
"description": "Cortisol. Maps to source symbol `cortisol`. Units: mcg_ml. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "acth_k4",
"label": "Acth K4",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.acth_k4",
"description": "Acth K4. Maps to source symbol `k4`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "acth_k5",
"label": "Acth K5",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.acth_k5",
"description": "Acth K5. Maps to source symbol `k5`. Units: flux. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "acth_k6",
"label": "Acth K6",
"maps_to": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.acth_k6",
"description": "Acth K6. Maps to source symbol `k6`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
}
]
},
"title": "Gonzalezheydrich1994 - Gonzalez Heydrich Mathematical Hpa Axis Lab",
"models": [
{
"path": "models/core",
"alias": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model",
"parameters": {
"model_path": "data/gonzalezheydrich_steingard_kohane_1994.cellml",
"integration_step": 0.01
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model_state"
],
"from": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.state"
},
{
"to": [
"visualisation.physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model_summary"
],
"from": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model_trajectory"
],
"from": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model_variable_labels"
],
"from": "physiology_cellml_gonzalezheydrich_steingard_kohane_1994_gonzalezheydrichsteingardkohane1994_model.variable_labels"
}
],
"package": "gonzalezheydrich1994-gonzalez-heydrich-mathematical-hpa-axis",
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"version": "1.0.0",
"description": "Source-faithful physiology lab for Gonzalezheydrich, Steingard, Kohane, 1994. Public controls and outputs are mapped to real source symbols for source-model physiology.",
"schema_version": "2.0"
}Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packagegonzalezheydrich1994-gonzalez-heydrich-mathematical-hpa-axis
Created2026-05-23
Updated2026-06-13
physiologycellmlphysiomefaithfulvisualisationother