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The model reproduces the compartmental model for Ran transport as depicted in Fig 3 of the paper. It can be used to explore systemsbiology smithae2002 rantransport BioModels0000000164 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_carrier_cytosol",
"label": "Initial Carrier Cytosol",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.initial_carrier_cytosol",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Carrier_Cytosol`."
},
{
"name": "initial_carrier_ran_gtp_nucleus",
"label": "Initial Carrier Ran Gtp Nucleus",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.initial_carrier_ran_gtp_nucleus",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Carrier_RanGTP_Nucleus`."
},
{
"name": "initial_carrier_nucleus",
"label": "Initial Carrier Nucleus",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.initial_carrier_nucleus",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Carrier_Nucleus`."
},
{
"name": "initial_ran_bp1_cytosol",
"label": "Initial Ran BP1 Cytosol",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.initial_ran_bp1_cytosol",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `RanBP1_Cytosol`."
},
{
"name": "initial_ran_gdp_cytosol",
"label": "Initial Ran Gdp Cytosol",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.initial_ran_gdp_cytosol",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `RanGDP_Cytosol`."
},
{
"name": "initial_ntf2_ran_gdp_cytosol",
"label": "Initial Ntf2 Ran Gdp Cytosol",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.initial_ntf2_ran_gdp_cytosol",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `NTF2_RanGDP_Cytosol`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.species_labels"
},
{
"name": "carrier_cytosol",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.carrier_cytosol"
},
{
"name": "carrier_ran_gtp_nucleus",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.carrier_ran_gtp_nucleus"
},
{
"name": "carrier_nucleus",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.carrier_nucleus"
},
{
"name": "ran_bp1_cytosol",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.ran_bp1_cytosol"
},
{
"name": "ran_gdp_cytosol",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.ran_gdp_cytosol"
},
{
"name": "ntf2_ran_gdp_cytosol",
"maps_to": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.ntf2_ran_gdp_cytosol"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Smithae2002 Rantransport Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model_state"
],
"from": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model_summary"
],
"from": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model_species_labels"
],
"from": "systemsbiology_sbml_smithae2002_rantransport_biomd0000000164_model.species_labels"
}
],
"package": "smithae2002-rantransport",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "The model reproduces the compartmental model for Ran transport as depicted in Fig 3 of the paper. It can be used to explore systemsbiology smithae2002 rantransport BioModels0000000164 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagesmithae2002-rantransport
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother