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The model reproduces the time profile of p53 and Mdm2 as depicted in Fig 6B of the plot for model 1. It can be used to explore systemsbiology zatorsky2006 p53 model1 BioModels0000000159 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_precursor_mdm2",
"label": "Initial Precursor Mdm2",
"maps_to": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.initial_precursor_mdm2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `y0`."
},
{
"name": "initial_model_state_p53",
"label": "Initial Model State P53",
"maps_to": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.initial_model_state_p53",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `x`."
},
{
"name": "initial_mdm2",
"label": "Initial Mdm2",
"maps_to": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.initial_mdm2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `y`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.species_labels"
},
{
"name": "precursor_mdm2",
"maps_to": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.precursor_mdm2"
},
{
"name": "p53",
"maps_to": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.p53"
},
{
"name": "mdm2",
"maps_to": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.mdm2"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Zatorsky2006 P53 Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model_state"
],
"from": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model_summary"
],
"from": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model_species_labels"
],
"from": "systemsbiology_sbml_zatorsky2006_p53_model1_biomd0000000159_model.species_labels"
}
],
"package": "zatorsky2006-p53",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "The model reproduces the time profile of p53 and Mdm2 as depicted in Fig 6B of the plot for model 1. It can be used to explore systemsbiology zatorsky2006 p53 model1 BioModels0000000159 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagezatorsky2006-p53
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother