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DallePezze2016 - Activation of AMPK and mTORby amino acids (Model 3) This model is as described in the Supplementary Software 3 of the reference publication: SBML model similar to Model S2, but includ. It can be used to explore systemsbiology dallepezze2016 activation of ampk and dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "ir_beta_phos_by_insulin",
"label": "Ir Beta Phos By Insulin",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.ir_beta_phos_by_insulin",
"description": "Source parameter exposed because its SBML label indicates a boundary, stimulus, dose, ligand, protocol, substrate, or environmental control. Maps to SBML symbol `IR_beta_phos_by_Insulin`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.species_labels"
},
{
"name": "p70_s6_k",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.p70_s6_k"
},
{
"name": "m_torc2",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.m_torc2"
},
{
"name": "m_torc1",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.m_torc1"
},
{
"name": "tsc1_tsc2",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.tsc1_tsc2"
},
{
"name": "pi3_k_variant",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.pi3_k_variant"
},
{
"name": "pi3_k_pdk1",
"maps_to": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.pi3_k_pdk1"
}
]
},
"tags": [
"signaling",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Dallepezze2016 Activation Of Ampk And Mtor By Amino Acids Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model_state"
],
"from": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model_summary"
],
"from": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model_species_labels"
],
"from": "systemsbiology_sbml_dallepezze2016_activation_of_ampk_and_mtor_by_am_biomd0000000640_model.species_labels"
}
],
"package": "dallepezze2016-activation-of-ampk-and-mtor-by-amino-acids",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "DallePezze2016 - Activation of AMPK and mTORby amino acids (Model 3) This model is as described in the Supplementary Software 3 of the reference publication: SBML model similar to Model S2, but includ. It can be used to explore systemsbiology dallepezze2016 activation of ampk and dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagedallepezze2016-activation-of-ampk-and-mtor-by-amino-acids
Created2026-05-17
Updated2026-06-13
signalingsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother