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Single-model lab wrapper for COVID-19 immunotherapy A mathematical model. The pandemic caused by SARS-CoV-2 is responsible for terrible health devastation with profoundly harmful consequences for the economic, social and political activities of communities on a global scale. It can be used to explore transmission dynamics and compare scenario outcomes across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "virus_clearance_rate",
"label": "Virus Clearance Rate",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.virus_clearance_rate"
},
{
"name": "virus_production_rate",
"label": "Virus Production Rate",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.virus_production_rate"
},
{
"name": "infected_cell_death_rate",
"label": "Infected Cell Death Rate",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.infected_cell_death_rate"
},
{
"name": "immune_activation_rate",
"label": "Immune Activation Rate",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.immune_activation_rate"
}
],
"outputs": [
{
"name": "state",
"label": "Model state",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.state"
},
{
"name": "summary",
"label": "Simulation summary",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.summary"
},
{
"name": "species_labels",
"label": "Species labels",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.species_labels"
},
{
"name": "treated_viral_load",
"label": "Treated viral load",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.treated_viral_load"
},
{
"name": "treated_free_virus",
"label": "Treated free virus",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.treated_free_virus"
},
{
"name": "treated_infected_epithelial_cells",
"label": "Treated infected epithelial cells",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.treated_infected_epithelial_cells"
},
{
"name": "treated_activated_neutrophils",
"label": "Treated activated neutrophils",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.treated_activated_neutrophils"
},
{
"name": "treated_interleukin_12",
"label": "Treated interleukin 12",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.treated_interleukin_12"
},
{
"name": "treated_antibody_response",
"label": "Treated antibody response",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.treated_antibody_response"
},
{
"name": "treated_b_cells",
"label": "Treated B cells",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.treated_b_cells"
},
{
"name": "treatment_inhibition_signal",
"label": "Treatment inhibition signal",
"maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.treatment_inhibition_signal"
}
]
},
"title": "COVID-19 Immunotherapy 2022 Treatment Model Lab",
"models": [
{
"path": "models/core",
"alias": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model",
"parameters": {
"model_path": "data/MODEL2202230002.xml",
"integration_step": 0.1
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model_state"
],
"from": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.state"
},
{
"to": [
"visualisation.epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model_summary"
],
"from": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.summary"
},
{
"to": [
"visualisation.epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model_species_labels"
],
"from": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2202230002_model.species_labels"
}
],
"package": "covidimmunotherapy2022-immune-treatment",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Single-model lab wrapper for COVID-19 immunotherapy A mathematical model. The pandemic caused by SARS-CoV-2 is responsible for terrible health devastation with profoundly harmful consequences for the economic, social and political activities of communities on a global scale. It can be used to explore transmission dynamics and compare scenario outcomes across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagecovidimmunotherapy2022-immune-treatment
Created2026-05-15
Updated2026-06-13
biomodels_ebicuratedepidemiologyfaithfulsbmltelluriumvisualisationother