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Source-faithful physiology lab for Chang, Fujita, 1999. Public controls and outputs are mapped to real source symbols for transport physiology.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_extracellular_transporter_sodium_chloride_complex",
"label": "Initial Extracellular Transporter Sodium Chloride Complex",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.initial_extracellular_transporter_sodium_chloride_complex",
"description": "Initial value for Extracellular Transporter Sodium Chloride Complex. Maps to source symbol `ENaCl`. Units: millimolar. Naming evidence: source metadata names `ENaCl` as `Extracellular Transporter-Sodium-Chloride Complex`.",
"accepted_units": [
"millimolar"
]
},
{
"name": "initial_chloride_concentration",
"label": "Initial Chloride Concentration (source ECl_)",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.initial_chloride_concentration",
"description": "Initial value for Chloride Concentration (source ECl_). Maps to source symbol `ECl_`. Units: millimolar. Naming evidence: chloride-like source symbol and concentration units support a conservative chloride concentration label.",
"accepted_units": [
"millimolar"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.variable_labels"
},
{
"name": "chloride_concentration",
"label": "Chloride Concentration (source ECl_)",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.chloride_concentration",
"description": "Chloride Concentration (source ECl_). Maps to source symbol `ECl_`. Units: millimolar. Naming evidence: chloride-like source symbol and concentration units support a conservative chloride concentration label."
},
{
"name": "extracellular_transporter_chloride_complex",
"label": "Extracellular Transporter Chloride Complex",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.extracellular_transporter_chloride_complex",
"description": "Extracellular Transporter Chloride Complex. Maps to source symbol `ECl`. Units: millimolar. Naming evidence: source metadata names `ECl` as `Extracellular Transporter-Chloride Complex`."
},
{
"name": "extracellular_transporter",
"label": "Extracellular Transporter",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.extracellular_transporter",
"description": "Extracellular Transporter. Maps to source symbol `E`. Units: millimolar. Naming evidence: source metadata names `E` as `Extracellular Transporter`."
},
{
"name": "intracellular_transporter",
"label": "Intracellular Transporter",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.intracellular_transporter",
"description": "Intracellular Transporter. Maps to source symbol `E_`. Units: millimolar. Naming evidence: source metadata names `E_` as `Intracellular Transporter`."
},
{
"name": "extracellular_transporter_thiazide_diuretics_complex",
"label": "Extracellular Transporter Thiazide Diuretics Complex",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.extracellular_transporter_thiazide_diuretics_complex",
"description": "Extracellular Transporter Thiazide Diuretics Complex. Maps to source symbol `ED`. Units: millimolar. Naming evidence: source metadata names `ED` as `Extracellular Transporter-Thiazide Diuretics Complex`."
},
{
"name": "intracellular_transporter_thiazide_diuretics_complex",
"label": "Intracellular Transporter Thiazide Diuretics Complex",
"maps_to": "physiology_cellml_chang_fujita_1999_changfujita1999_model.intracellular_transporter_thiazide_diuretics_complex",
"description": "Intracellular Transporter Thiazide Diuretics Complex. Maps to source symbol `ED_`. Units: millimolar. Naming evidence: source metadata names `ED_` as `Intracellular Transporter-Thiazide Diuretics Complex`."
}
]
},
"title": "Chang1999 - Fujita Kinetic Thiazide Sensitive Na Cl Cotransporter Lab",
"models": [
{
"path": "models/core",
"alias": "physiology_cellml_chang_fujita_1999_changfujita1999_model",
"parameters": {
"model_path": "data/chang_fujita_1999.cellml",
"integration_step": 0.01
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_chang_fujita_1999_changfujita1999_model_state"
],
"from": "physiology_cellml_chang_fujita_1999_changfujita1999_model.state"
},
{
"to": [
"visualisation.physiology_cellml_chang_fujita_1999_changfujita1999_model_summary"
],
"from": "physiology_cellml_chang_fujita_1999_changfujita1999_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_chang_fujita_1999_changfujita1999_model_trajectory"
],
"from": "physiology_cellml_chang_fujita_1999_changfujita1999_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_chang_fujita_1999_changfujita1999_model_variable_labels"
],
"from": "physiology_cellml_chang_fujita_1999_changfujita1999_model.variable_labels"
}
],
"package": "chang1999-fujita-kinetic-thiazide-sensitive-na-cl-cotransporter",
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"version": "1.0.0",
"description": "Source-faithful physiology lab for Chang, Fujita, 1999. Public controls and outputs are mapped to real source symbols for transport physiology.",
"schema_version": "2.0"
}Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packagechang1999-fujita-kinetic-thiazide-sensitive-na-cl-cotransporter
Created2026-05-23
Updated2026-06-13
physiologycellmlphysiomefaithfulvisualisationother