Bhalla2004 Ajay Pkm Tuning Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_egfr_slash_internal_l_dot_egfr",
        "label": "Initial EGFR Slash Internal L Dot EGFR",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.initial_egfr_slash_internal_l_dot_egfr",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `EGFR_slash_Internal_L_dot_EGFR`."
      },
      {
        "name": "initial_ac_slash_atp",
        "label": "Initial Ac Slash ATP",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.initial_ac_slash_atp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `AC_slash_ATP`."
      },
      {
        "name": "initial_mapk_slash_mapk",
        "label": "Initial MAPK Slash MAPK",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.initial_mapk_slash_mapk",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `MAPK_slash_MAPK`."
      },
      {
        "name": "initial_ras_slash_gdp_minus_ras",
        "label": "Initial RAS Slash Gdp Minus RAS",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.initial_ras_slash_gdp_minus_ras",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ras_slash_GDP_minus_Ras`."
      },
      {
        "name": "initial_mapk_slash_mapkk",
        "label": "Initial MAPK Slash Mapkk",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.initial_mapk_slash_mapkk",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `MAPK_slash_MAPKK`."
      },
      {
        "name": "initial_mapk_slash_craf_minus_1",
        "label": "Initial MAPK Slash Craf Minus 1",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.initial_mapk_slash_craf_minus_1",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `MAPK_slash_craf_minus_1`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.species_labels"
      },
      {
        "name": "egfr_slash_internal_l_dot_egfr",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.egfr_slash_internal_l_dot_egfr"
      },
      {
        "name": "ac_slash_atp",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.ac_slash_atp"
      },
      {
        "name": "mapk_slash_mapk",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.mapk_slash_mapk"
      },
      {
        "name": "ras_slash_gdp_minus_ras",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.ras_slash_gdp_minus_ras"
      },
      {
        "name": "mapk_slash_mapkk",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.mapk_slash_mapkk"
      },
      {
        "name": "mapk_slash_craf_minus_1",
        "maps_to": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.mapk_slash_craf_minus_1"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Bhalla2004 Ajay Pkm Tuning Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model_state"
      ],
      "from": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model_summary"
      ],
      "from": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model_species_labels"
      ],
      "from": "systemsbiology_sbml_ajay_bhalla_2004_pkm_tuning_model9089491423_model.species_labels"
    }
  ],
  "package": "bhalla2004-ajay-pkm-tuning",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "This model is taken from the <a href = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15548210&query_hl=1&itool=pubmed_docsum'&. It can be used to explore systemsbiology ajay bhalla 2004 pkm tuning dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}