Dritschel2018 - A mathematical model of cytotoxic and helper T cell interactions in a tumour microenvironment Lab
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This model examines the role of helper and cytotoxic T cells in an anti-tumour response, with implicit inclusions of immunosuppressive effects. The model demonstrates the dependence of immunoediting o.
Manifest
{
"io": {
"inputs": [
{
"name": "ntilde_source_parameter",
"label": "Ntilde source parameter",
"units": "native SBML value",
"default": 0.04,
"maps_to": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.ntilde_source_parameter",
"description": "Ntilde source parameter. Maps to bundled SBML parameter `Ntilde`."
},
{
"name": "initial_n_tumor",
"label": "N Tumour",
"units": "native SBML value",
"default": 0.01,
"maps_to": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.initial_n_tumor",
"description": "Initial N Tumour. Sets the initial value of bundled SBML symbol `N_Tumour`."
}
],
"outputs": [
{
"name": "n_tumor",
"maps_to": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.n_tumor",
"description": "N Tumour observable. Maps to SBML symbol `N_Tumour`."
},
{
"name": "t_h",
"maps_to": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.t_h",
"description": "T H observable. Maps to SBML symbol `T_H`."
},
{
"name": "t_c",
"maps_to": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.t_c",
"description": "T C observable. Maps to SBML symbol `T_C`."
},
{
"name": "state",
"maps_to": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"faithful",
"immunology",
"immunotherapy",
"microenvironment",
"oncology",
"physiology",
"sbml",
"systemsbiology",
"tumor-growth"
],
"title": "Dritschel2018 - A mathematical model of cytotoxic and helper T cell interactions in a tumour microenvironment Lab",
"models": [
{
"path": "models/core",
"alias": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model_state"
],
"from": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.state"
},
{
"to": [
"visualisation.oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model_summary"
],
"from": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model_species_labels"
],
"from": "oncology_sbml_dritschel2018_a_mathematical_model_of_cytotoxic_biomd0000000763_model.species_labels"
}
],
"package": "dritschel2018-a-mathematical-of-cytotoxic-and-helper-t-568b90ff",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This model examines the role of helper and cytotoxic T cells in an anti-tumour response, with implicit inclusions of immunosuppressive effects. The model demonstrates the dependence of immunoediting o.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagedritschel2018-a-mathematical-of-cytotoxic-and-helper-t-568b90ff
Created2026-05-16
Updated2026-06-13
biomodels_ebicuratedfaithfulimmunologyimmunotherapymicroenvironmentoncologyphysiologysbmlsystemsbiologytumor-growthvisualisationother