Banerjee2015 - A Mathematical Model to Elucidate BrainTumor Abrogation by Immunotherapywith T11 Target Structure Lab
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T11 Target structure (T11TS), a membrane glycoprotein isolated from sheep erythrocytes, reverses the immune suppressed state of brain tumor induced animals by boosting the functional status of the imm. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_unresolved_tumor_observable_1",
"label": "Initial Unresolved Tumor Observable 1",
"units": "native source value",
"default": 857419,
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_1",
"description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `G`."
},
{
"name": "initial_unresolved_tumor_observable_2",
"label": "Initial Unresolved Tumor Observable 2",
"units": "native source value",
"default": 943092,
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_2",
"description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `M`."
},
{
"name": "initial_unresolved_tumor_observable_3",
"label": "Initial Unresolved Tumor Observable 3",
"units": "native source value",
"default": 303.397,
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_3",
"description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `CT`."
},
{
"name": "initial_unresolved_tumor_observable_4",
"label": "Initial Unresolved Tumor Observable 4",
"units": "native source value",
"default": 9134.33,
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_4",
"description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `TB`."
},
{
"name": "initial_unresolved_tumor_observable_5",
"label": "Initial Unresolved Tumor Observable 5",
"units": "native source value",
"default": 0.303397,
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_5",
"description": "Initial Unresolved Tumor Observable 5. Sets the initial value of bundled SBML species `IG`."
},
{
"name": "cytokine_transforming_growth_factor_beta_removal_rate",
"label": "Cytokine Transforming Growth Factor Beta Removal Rate",
"units": "native source value",
"default": 6.93,
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.cytokine_transforming_growth_factor_beta_removal_rate",
"description": "Cytokine Transforming Growth Factor Beta Removal Rate. Sets bundled SBML parameter `mu_2`."
}
],
"outputs": [
{
"name": "unresolved_tumor_observable_1",
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_1"
},
{
"name": "unresolved_tumor_observable_2",
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_2"
},
{
"name": "unresolved_tumor_observable_3",
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_3"
},
{
"name": "unresolved_tumor_observable_4",
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_4"
},
{
"name": "unresolved_tumor_observable_5",
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_5"
},
{
"name": "state",
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.species_labels"
}
]
},
"title": "Banerjee2015 - A Mathematical Model to Elucidate BrainTumor Abrogation by Immunotherapywith T11 Target Structure Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model_state"
],
"from": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.state"
},
{
"to": [
"visualisation.immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model_summary"
],
"from": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model_species_labels"
],
"from": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.species_labels"
}
],
"package": "banerjee2015-a-mathematical-model-to-elucidate-braintum-a3e3ac6a",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.1",
"description": "T11 Target structure (T11TS), a membrane glycoprotein isolated from sheep erythrocytes, reverses the immune suppressed state of brain tumor induced animals by boosting the functional status of the imm. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagebanerjee2015-a-mathematical-model-to-elucidate-braintum-a3e3ac6a
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother