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This is a mathematical model describing the imbalance between T helper (Th1/Th2) cell types in melanome patients, together with its regulation via IL-12 treatment. It can be used to explore systemsbiology kogan2013 a mathematical for the dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_model_state_t_2",
"label": "Initial Model State T 2",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.initial_model_state_t_2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T_2`."
},
{
"name": "initial_model_state_t_1",
"label": "Initial Model State T 1",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.initial_model_state_t_1",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T_1`."
},
{
"name": "initial_model_state_i",
"label": "Initial Model State I",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.initial_model_state_i",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `I`."
},
{
"name": "initial_model_state_g",
"label": "Initial Model State G",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.initial_model_state_g",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `G`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.summary"
},
{
"name": "species_labels",
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},
{
"name": "t_2",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.t_2"
},
{
"name": "t_1",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.t_1"
},
{
"name": "model_state_i",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.model_state_i"
},
{
"name": "model_state_g",
"maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.model_state_g"
}
]
},
"tags": [
"oncology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Kogan2013 A Mathematical Model For The Immunotherapeutic Control Of Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
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},
{
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}
],
"package": "kogan2013-a-mathematical-model-for-the-immunotherapeuti-e4a1a432",
"runtime": {
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"initial_inputs": {},
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},
"version": "1.0.0",
"description": "This is a mathematical model describing the imbalance between T helper (Th1/Th2) cell types in melanome patients, together with its regulation via IL-12 treatment. It can be used to explore systemsbiology kogan2013 a mathematical for the dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagekogan2013-a-mathematical-model-for-the-immunotherapeuti-e4a1a432
Created2026-05-17
Updated2026-06-13
oncologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother