Mueller2015 - Hepatocyte proliferation, T160 phosphorylation of CDK2 Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cdk2p21",
        "label": "Initial CDK2P21",
        "maps_to": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.initial_cdk2p21",
        "description": "Initial level of CDK2P21. Maps to SBML symbol `ObsCDK2P21_obs`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_dnacontent",
        "label": "Initial Dnacontent",
        "maps_to": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.initial_dnacontent",
        "description": "Initial level of Dnacontent. Maps to SBML symbol `ObsDNAContent_obs`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_source_defined_hgf_state",
        "label": "Initial source-defined HGF state",
        "maps_to": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.initial_source_defined_hgf_state",
        "description": "Initial level of source-defined HGF state. Maps to SBML symbol `hgf`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "inh_erk",
        "label": "Inh ERK",
        "maps_to": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.inh_erk",
        "description": "Inh ERK. Maps to SBML symbol `inherk` and is emitted in native SBML units."
      },
      {
        "name": "inh_akt",
        "label": "Inh AKT",
        "maps_to": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.inh_akt",
        "description": "Inh AKT. Maps to SBML symbol `inhakt` and is emitted in native SBML units."
      },
      {
        "name": "cyto_c2e_t160_u_b",
        "label": "Cyto C2E T160 U B",
        "maps_to": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.cyto_c2e_t160_u_b",
        "description": "Cyto C2E T160 U B. Maps to SBML symbol `S4` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "cell-cycle-signaling"
  ],
  "title": "Mueller2015 - Hepatocyte proliferation, T160 phosphorylation of CDK2 Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model_state"
      ],
      "from": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model_summary"
      ],
      "from": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model_species_labels"
      ],
      "from": "signaling_sbml_mueller2015_hepatocyte_proliferation_t160_phosph_biomd0000000568_model.species_labels"
    }
  ],
  "package": "mueller2015-hepatocyte-proliferation-t160-phosph",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for cell-cycle regulatory signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}