Muller2008 - Network Topology Determines Dynamics Mammalian Mapk1 2 Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_c_raf_inactive",
        "label": "Initial C Raf Inactive",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.initial_c_raf_inactive",
        "description": "Initial value for C Raf Inactive. Maps to source symbol `y6`. Units: micromolar. Naming evidence: source metadata names `y6` as `C-Raf inactive`.",
        "accepted_units": [
          "micromolar"
        ]
      },
      {
        "name": "initial_fgfr",
        "label": "Initial Fgfr",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.initial_fgfr",
        "description": "Initial value for Fgfr. Maps to source symbol `y1`. Units: micromolar. Naming evidence: source metadata names `y1` as `FGFR`.",
        "accepted_units": [
          "micromolar"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.variable_labels"
      },
      {
        "name": "c_raf_inactive",
        "label": "C Raf Inactive",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.c_raf_inactive",
        "description": "C Raf Inactive. Maps to source symbol `y6`. Units: micromolar. Naming evidence: source metadata names `y6` as `C-Raf inactive`."
      },
      {
        "name": "fgfr",
        "label": "Fgfr",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.fgfr",
        "description": "Fgfr. Maps to source symbol `y1`. Units: micromolar. Naming evidence: source metadata names `y1` as `FGFR`."
      },
      {
        "name": "mapk",
        "label": "Mapk",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.mapk",
        "description": "Mapk. Maps to source symbol `y5`. Units: micromolar. Naming evidence: source metadata names `y5` as `MAPK`."
      },
      {
        "name": "msh",
        "label": "Msh",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.msh",
        "description": "Msh. Maps to source symbol `y2`. Units: micromolar. Naming evidence: source metadata names `y2` as `MSH`."
      },
      {
        "name": "b_raf",
        "label": "B Raf",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.b_raf",
        "description": "B Raf. Maps to source symbol `y4`. Units: micromolar. Naming evidence: source metadata names `y4` as `B-Raf`."
      },
      {
        "name": "c_raf",
        "label": "C Raf",
        "maps_to": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.c_raf",
        "description": "C Raf. Maps to source symbol `y3`. Units: micromolar. Naming evidence: source metadata names `y3` as `C-Raf`."
      }
    ]
  },
  "title": "Muller2008 - Network Topology Determines Dynamics Mammalian Mapk1 2 Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model",
      "parameters": {
        "model_path": "data/muller_obeyesekere_mills_ram_2008.cellml",
        "integration_step": 0.01
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model_state"
      ],
      "from": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model_summary"
      ],
      "from": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model_trajectory"
      ],
      "from": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model_variable_labels"
      ],
      "from": "physiology_cellml_muller_obeyesekere_mills_ram_2008_mullerobeyesekeremillsram2008_model.variable_labels"
    }
  ],
  "package": "muller2008-network-topology-determines-dynamics-mammali-c07ff41f",
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "version": "1.0.0",
  "description": "Source-faithful physiology lab for Muller, Obeyesekere, Mills, Ram, 2008. Public controls and outputs are mapped to real source symbols for signalling physiology.",
  "schema_version": "2.0"
}