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One published Lab
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Model reproduces the various plots in the publication for 'Control' concentrations. It can be used to explore systemsbiology ung2008 egfr endocytosis BioModels0000000205 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_pro_egfr",
"label": "Initial Pro EGFR",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.initial_pro_egfr",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_122`."
},
{
"name": "initial_model_state_shc",
"label": "Initial Model State Shc",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.initial_model_state_shc",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_7`."
},
{
"name": "initial_m_pase",
"label": "Initial M Pase",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.initial_m_pase",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_125`."
},
{
"name": "initial_grb2",
"label": "Initial Grb2",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.initial_grb2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_12`."
},
{
"name": "initial_cbl_cin85",
"label": "Initial Cbl Cin85",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.initial_cbl_cin85",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_114`."
},
{
"name": "initial_model_state_rok",
"label": "Initial Model State Rok",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.initial_model_state_rok",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_105`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.species_labels"
},
{
"name": "pro_egfr",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.pro_egfr"
},
{
"name": "shc",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.shc"
},
{
"name": "m_pase",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.m_pase"
},
{
"name": "grb2",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.grb2"
},
{
"name": "cbl_cin85",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.cbl_cin85"
},
{
"name": "rok",
"maps_to": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.rok"
}
]
},
"tags": [
"cellcycle",
"signaling",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Ung2008 Egfr Endocytosis Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model_state"
],
"from": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model_summary"
],
"from": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model_species_labels"
],
"from": "systemsbiology_sbml_ung2008_egfr_endocytosis_biomd0000000205_model.species_labels"
}
],
"package": "ung2008-egfr-endocytosis",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Model reproduces the various plots in the publication for 'Control' concentrations. It can be used to explore systemsbiology ung2008 egfr endocytosis BioModels0000000205 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageung2008-egfr-endocytosis
Created2026-05-17
Updated2026-06-13
cellcyclesignalingsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother