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Basic mathematical model of the formation of coagulation factor Xa involving TF:VIIa and its inhibition by TFPI. It can be used to explore systemsbiology baugh1998 regulation of coagulation factor dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_model_state_p_i",
"label": "Initial Model State P I",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_p_i",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `P_I`."
},
{
"name": "initial_ep_i",
"label": "Initial Ep I",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_ep_i",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `EP_I`."
},
{
"name": "initial_model_state_es",
"label": "Initial Model State Es",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_es",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ES`."
},
{
"name": "initial_model_state_s",
"label": "Initial Model State S",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_s",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `S`."
},
{
"name": "initial_model_state_i",
"label": "Initial Model State I",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_i",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `I`."
},
{
"name": "initial_model_state_e",
"label": "Initial Model State E",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_e",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `E`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.species_labels"
},
{
"name": "p_i",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.p_i"
},
{
"name": "ep_i",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.ep_i"
},
{
"name": "model_state_es",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.model_state_es"
},
{
"name": "model_state_s",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.model_state_s"
},
{
"name": "model_state_i",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.model_state_i"
},
{
"name": "model_state_e",
"maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.model_state_e"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Baugh1998 Regulation Of Coagulation Factor Xa By Tfpi Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model_state"
],
"from": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model_summary"
],
"from": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model_species_labels"
],
"from": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.species_labels"
}
],
"package": "baugh1998-regulation-of-coagulation-factor-xa-by-tfpi",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Basic mathematical model of the formation of coagulation factor Xa involving TF:VIIa and its inhibition by TFPI. It can be used to explore systemsbiology baugh1998 regulation of coagulation factor dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagebaugh1998-regulation-of-coagulation-factor-xa-by-tfpi
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother