Sluka2016 - Acetaminophen PBPK Lab

{
  "io": {
    "inputs": [
      {
        "name": "acetaminophen_dose_grams",
        "label": "Acetaminophen Dose Grams",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.acetaminophen_dose_grams"
      },
      {
        "name": "initial_gut_lumen_acetaminophen",
        "label": "Initial Gut Lumen Acetaminophen",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.initial_gut_lumen_acetaminophen"
      },
      {
        "name": "initial_liver_acetaminophen_concentration",
        "label": "Initial Liver Acetaminophen Concentration",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.initial_liver_acetaminophen_concentration"
      },
      {
        "name": "initial_metabolized_acetaminophen",
        "label": "Initial Metabolized Acetaminophen",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.initial_metabolized_acetaminophen"
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Tracked source state",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.species_labels"
      },
      {
        "name": "liver_acetaminophen_concentration",
        "label": "Liver Acetaminophen Concentration",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.liver_acetaminophen_concentration"
      },
      {
        "name": "arterial_acetaminophen_concentration",
        "label": "Arterial Acetaminophen Concentration",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.arterial_acetaminophen_concentration"
      },
      {
        "name": "gut_acetaminophen_concentration",
        "label": "Gut Acetaminophen Concentration",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.gut_acetaminophen_concentration"
      },
      {
        "name": "gut_lumen_acetaminophen_amount",
        "label": "Gut Lumen Acetaminophen Amount",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.gut_lumen_acetaminophen_amount"
      },
      {
        "name": "lung_acetaminophen_concentration",
        "label": "Lung Acetaminophen Concentration",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.lung_acetaminophen_concentration"
      },
      {
        "name": "venous_acetaminophen_concentration",
        "label": "Venous Acetaminophen Concentration",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.venous_acetaminophen_concentration"
      },
      {
        "name": "rest_body_acetaminophen_concentration",
        "label": "Rest Body Acetaminophen Concentration",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.rest_body_acetaminophen_concentration"
      },
      {
        "name": "metabolized_acetaminophen_concentration",
        "label": "Metabolized Acetaminophen Concentration",
        "maps_to": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.metabolized_acetaminophen_concentration"
      }
    ]
  },
  "tags": [
    "pharmacology",
    "pbpk",
    "pharmacokinetics",
    "toxicology",
    "liver",
    "sbml",
    "tellurium",
    "faithful",
    "biomodels_ebi"
  ],
  "title": "Sluka2016 - Acetaminophen PBPK Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model",
      "parameters": {
        "model_path": "data/BIOMD0000000619.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model_state"
      ],
      "from": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.state"
    },
    {
      "to": [
        "visualisation.pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model_summary"
      ],
      "from": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.summary"
    },
    {
      "to": [
        "visualisation.pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model_species_labels"
      ],
      "from": "pharmacology_sbml_sluka2016_acetaminophen_pbpk_biomd0000000619_model.species_labels"
    }
  ],
  "package": "sluka2016-acetaminophen-pbpk",
  "runtime": {
    "duration": 24,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Basic PBPK (Physiologically Based PharmacoKinetic) model of Acetaminophen. This is a basic model of Acetaminophen (APAP, Paracetamol) pharmacokinetics in humans.",
  "schema_version": "2.0"
}