About lab
One published Lab
Build with this Lab. Run it anywhere.
Use the same immutable release locally or through managed cloud execution, with its exact version and provenance preserved.
Preparing exact examples…
This a model from the article: Experimental and computational analysis of polyglutamine-mediated cytotoxicity. Tang MY, Proctor CJ, Woulfe J, Gray DA.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_nat_p",
"label": "Initial Nat P",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.initial_nat_p",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `NatP`."
},
{
"name": "initial_p_ideath",
"label": "Initial P Ideath",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.initial_p_ideath",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `PIdeath`."
},
{
"name": "initial_p38death",
"label": "Initial P38death",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.initial_p38death",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `p38death`."
},
{
"name": "initial_proteasome",
"label": "Initial Proteasome",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.initial_proteasome",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Proteasome`."
},
{
"name": "initial_poly_q",
"label": "Initial Poly Q",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.initial_poly_q",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `PolyQ`."
},
{
"name": "initial_mrf_pu",
"label": "Initial Mrf Pu",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.initial_mrf_pu",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mRFPu`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.species_labels"
},
{
"name": "nat_p",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.nat_p"
},
{
"name": "p_ideath",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.p_ideath"
},
{
"name": "p38death",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.p38death"
},
{
"name": "proteasome",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.proteasome"
},
{
"name": "poly_q",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.poly_q"
},
{
"name": "mrf_pu",
"maps_to": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.mrf_pu"
}
]
},
"tags": [
"cellcycle",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Tang2010 Polyglutamate Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model_state"
],
"from": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model_summary"
],
"from": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model_species_labels"
],
"from": "systemsbiology_sbml_tang2010_polyglutamate_biomd0000000285_model.species_labels"
}
],
"package": "tang2010-polyglutamate",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This a model from the article: Experimental and computational analysis of polyglutamine-mediated cytotoxicity. Tang MY, Proctor CJ, Woulfe J, Gray DA.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagetang2010-polyglutamate
Created2026-05-17
Updated2026-06-13
cellcyclesystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother