Hardiansyah2019 - QSP model of chimeric antigen receptor T-Cell therapy Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_immune_observable_1",
        "label": "Initial Unresolved Immune Observable 1",
        "units": "native source value",
        "default": 11000000000,
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.initial_unresolved_immune_observable_1",
        "description": "Initial Unresolved Immune Observable 1. Sets the initial value of bundled SBML species `B_pb`."
      },
      {
        "name": "initial_carte_pb",
        "label": "Initial Carte Pb",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.initial_carte_pb",
        "description": "Initial Carte Pb. Sets the initial value of bundled SBML species `CARTE_pb`."
      },
      {
        "name": "initial_interleukin_6",
        "label": "Initial Interleukin 6",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.initial_interleukin_6",
        "description": "Initial Interleukin 6. Sets the initial value of bundled SBML species `IL6`."
      },
      {
        "name": "initial_interleukin_10",
        "label": "Initial Interleukin 10",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.initial_interleukin_10",
        "description": "Initial Interleukin 10. Sets the initial value of bundled SBML species `IL10`."
      },
      {
        "name": "initial_interferon_gamma",
        "label": "Initial Interferon Gamma",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.initial_interferon_gamma",
        "description": "Initial Interferon Gamma. Sets the initial value of bundled SBML species `IFNg`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_immune_observable_1",
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.unresolved_immune_observable_1"
      },
      {
        "name": "carte_pb",
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.carte_pb"
      },
      {
        "name": "interleukin_6",
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.interleukin_6"
      },
      {
        "name": "interleukin_10",
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.interleukin_10"
      },
      {
        "name": "interferon_gamma",
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.interferon_gamma"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.species_labels"
      }
    ]
  },
  "title": "Hardiansyah2019 - QSP model of chimeric antigen receptor T-Cell therapy Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model_state"
      ],
      "from": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model_summary"
      ],
      "from": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model_species_labels"
      ],
      "from": "immunology_sbml_hardiansyah2019_qsp_model_of_chimeric_antigen_re_model2009230001_model.species_labels"
    }
  ],
  "package": "hardiansyah2019-qsp-model-of-chimeric-antigen-receptor-t",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This QSP model explains how the mechanism of action connects to the clinical outcomes and, therefore, may serve as an important model-based platform to guide the development and personalized dosing of. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}