Kotte2010_Ecoli_Metabolic_Adaption Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_microbial_metabolism_state_1",
        "units": "native SBML value",
        "default": 0.03,
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.initial_microbial_metabolism_state_1",
        "description": "Initial condition for microbial metabolism state 1. Maps to bundled SBML symbol `BM`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_microbial_metabolism_state_2",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.initial_microbial_metabolism_state_2",
        "description": "Initial condition for microbial metabolism state 2. Maps to bundled SBML symbol `ACT`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_glucose",
        "units": "native SBML value",
        "default": 4.8,
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.initial_glucose",
        "description": "Initial condition for glucose. Maps to bundled SBML symbol `GLC`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_microbial_metabolism_state_4",
        "units": "native SBML value",
        "default": 0.351972298,
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.initial_microbial_metabolism_state_4",
        "description": "Initial condition for microbial metabolism state 4. Maps to bundled SBML symbol `ACoA`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_microbial_metabolism_state_5",
        "units": "native SBML value",
        "default": 0.191190619,
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.initial_microbial_metabolism_state_5",
        "description": "Initial condition for microbial metabolism state 5. Maps to bundled SBML symbol `AKG`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "microbial_metabolism_state_1",
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.microbial_metabolism_state_1"
      },
      {
        "name": "microbial_metabolism_state_2",
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.microbial_metabolism_state_2"
      },
      {
        "name": "glucose",
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.glucose"
      },
      {
        "name": "microbial_metabolism_state_4",
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.microbial_metabolism_state_4"
      },
      {
        "name": "microbial_metabolism_state_5",
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.microbial_metabolism_state_5"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.observable_labels"
      }
    ]
  },
  "title": "Kotte2010_Ecoli_Metabolic_Adaption Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model",
      "parameters": {
        "model_path": "data/BIOMD0000000244.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model_observable_values"
      ],
      "from": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model_run_summary"
      ],
      "from": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model_observable_labels"
      ],
      "from": "metabolism_sbml_kotte2010_ecoli_metabolic_adaption_biomd0000000244_model.observable_labels"
    }
  ],
  "package": "kotte2010-ecoli-metabolic-adaption",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This is the model described in: Bacterial adaptation through distributed sensing of metabolic fluxes Oliver Kotte, Judith B Zaugg and Matthias Heinemann; Mol Sys Biol 2010; 6 :355. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.",
  "schema_version": "2.0"
}