Bexkens2024 - Schistosoma mansoni glycolysis Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_atp",
        "units": "native SBML value",
        "default": 1.18,
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.initial_atp",
        "description": "Initial condition for atp. Maps to bundled SBML symbol `ATP`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_intracellular_glucose",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.initial_intracellular_glucose",
        "description": "Initial condition for intracellular glucose. Maps to bundled SBML symbol `GLCi`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_adp",
        "units": "native SBML value",
        "default": 1.74,
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.initial_adp",
        "description": "Initial condition for adp. Maps to bundled SBML symbol `ADP`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_glucose_6_phosphate",
        "units": "native SBML value",
        "default": 0.00384,
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.initial_glucose_6_phosphate",
        "description": "Initial condition for glucose 6 phosphate. Maps to bundled SBML symbol `G6P`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_fructose_6_phosphate",
        "units": "native SBML value",
        "default": 0.00118,
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.initial_fructose_6_phosphate",
        "description": "Initial condition for fructose 6 phosphate. Maps to bundled SBML symbol `F6P`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "atp",
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.atp"
      },
      {
        "name": "intracellular_glucose",
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.intracellular_glucose"
      },
      {
        "name": "adp",
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.adp"
      },
      {
        "name": "glucose_6_phosphate",
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.glucose_6_phosphate"
      },
      {
        "name": "fructose_6_phosphate",
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.fructose_6_phosphate"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.observable_labels"
      }
    ]
  },
  "title": "Bexkens2024 - Schistosoma mansoni glycolysis Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model",
      "parameters": {
        "model_path": "data/MODEL2208290002.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model_observable_values"
      ],
      "from": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model_run_summary"
      ],
      "from": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model_observable_labels"
      ],
      "from": "metabolism_sbml_bexkens2024_schistosoma_mansoni_glycolysis_model2208290002_model.observable_labels"
    }
  ],
  "package": "bexkens2024-schistosoma-mansoni-glycolysis",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "A kinetic model of S. mansoni glycolysis in which we can vary the allosteric regulation on lactate dehydrogenase (LDH).",
  "schema_version": "2.0"
}