Jarrett2015 - Modelling the interaction between immune response, bacterial dynamics and inflammatory damage Lab
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Mathematical model of pro- and anti-inflammatory response, inflammation/damage and infection dynamics in BALB/c mouse with Staphylococcal aureus infection. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_bacterial_infection_b",
"label": "Initial Bacterial Infection B",
"units": "native source value",
"default": 1,
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.initial_bacterial_infection_b",
"description": "Initial Bacterial Infection B. Sets the initial value of bundled SBML species `bacterial_infection__B`."
},
{
"name": "initial_anti_inflammatory_a",
"label": "Initial Anti Inflammatory A",
"units": "native source value",
"default": 3,
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.initial_anti_inflammatory_a",
"description": "Initial Anti Inflammatory A. Sets the initial value of bundled SBML species `anti_inflammatory__A`."
},
{
"name": "initial_inflammation_i",
"label": "Initial Inflammation I",
"units": "native source value",
"default": 1,
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.initial_inflammation_i",
"description": "Initial Inflammation I. Sets the initial value of bundled SBML species `inflammation__I`."
},
{
"name": "initial_pro_inflammatory_p",
"label": "Initial Pro Inflammatory P",
"units": "native source value",
"default": 1,
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.initial_pro_inflammatory_p",
"description": "Initial Pro Inflammatory P. Sets the initial value of bundled SBML species `pro_inflammatory__P`."
}
],
"outputs": [
{
"name": "bacterial_infection_b",
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.bacterial_infection_b"
},
{
"name": "anti_inflammatory_a",
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.anti_inflammatory_a"
},
{
"name": "inflammation_i",
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.inflammation_i"
},
{
"name": "pro_inflammatory_p",
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.pro_inflammatory_p"
},
{
"name": "state",
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.species_labels"
}
]
},
"title": "Jarrett2015 - Modelling the interaction between immune response, bacterial dynamics and inflammatory damage Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model_state"
],
"from": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.state"
},
{
"to": [
"visualisation.immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model_summary"
],
"from": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model_species_labels"
],
"from": "immunology_sbml_jarrett2015_modelling_the_interaction_between_im_biomd0000000920_model.species_labels"
}
],
"package": "jarrett2015-modelling-the-interaction-between-immune-re-d2189f3a",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Mathematical model of pro- and anti-inflammatory response, inflammation/damage and infection dynamics in BALB/c mouse with Staphylococcal aureus infection. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagejarrett2015-modelling-the-interaction-between-immune-re-d2189f3a
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother