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Proctor2007 - Age related decline of proteolysis, ubiquitin-proteome system This is a stochastic model of the ubiquitin-proteasome system for a generic pool of native proteins (NatP), which have a hal. It can be used to explore systemsbiology proctor2007 age related decline of dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_model_state_atp",
"label": "Initial Model State ATP",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.initial_model_state_atp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ATP`."
},
{
"name": "initial_model_state_amp",
"label": "Initial Model State AMP",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.initial_model_state_amp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `AMP`."
},
{
"name": "initial_model_state_adp",
"label": "Initial Model State ADP",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.initial_model_state_adp",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ADP`."
},
{
"name": "initial_model_state_ub",
"label": "Initial Model State Ub",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.initial_model_state_ub",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ub`."
},
{
"name": "initial_nat_p",
"label": "Initial Nat P",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.initial_nat_p",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `NatP`."
},
{
"name": "initial_model_state_dub",
"label": "Initial Model State Dub",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.initial_model_state_dub",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `DUB`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.species_labels"
},
{
"name": "atp",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.atp"
},
{
"name": "amp",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.amp"
},
{
"name": "adp",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.adp"
},
{
"name": "model_state_ub",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.model_state_ub"
},
{
"name": "nat_p",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.nat_p"
},
{
"name": "dub",
"maps_to": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.dub"
}
]
},
"tags": [
"generegulation",
"metabolism",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Proctor2007 Age Related Decline Of Proteolysis Ubiquitin Proteome Syst Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model_state"
],
"from": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model_summary"
],
"from": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model_species_labels"
],
"from": "systemsbiology_sbml_proctor2007_age_related_decline_of_proteolysis_u_biomd0000000105_model.species_labels"
}
],
"package": "proctor2007-age-related-decline-of-proteolysis-ubiquiti-d992d64f",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Proctor2007 - Age related decline of proteolysis, ubiquitin-proteome system This is a stochastic model of the ubiquitin-proteasome system for a generic pool of native proteins (NatP), which have a hal. It can be used to explore systemsbiology proctor2007 age related decline of dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageproctor2007-age-related-decline-of-proteolysis-ubiquiti-d992d64f
Created2026-05-17
Updated2026-06-13
generegulationmetabolismsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother