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Clean Biosimulant lab for MAPK/ERK receptor signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_hr_inact",
"label": "Initial HR Inact",
"maps_to": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.initial_hr_inact",
"description": "Initial level of HR Inact. Maps to SBML symbol `species_11`; exposed as a traceable initial-condition perturbation."
},
{
"name": "initial_mek_act",
"label": "Initial MEK Act",
"maps_to": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.initial_mek_act",
"description": "Initial level of MEK Act. Maps to SBML symbol `species_14`; exposed as a traceable initial-condition perturbation."
},
{
"name": "initial_p_erk_c",
"label": "Initial P ERK C",
"maps_to": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.initial_p_erk_c",
"description": "Initial level of P ERK C. Maps to SBML symbol `species_13`; exposed as a traceable initial-condition perturbation."
}
],
"outputs": [
{
"name": "nuclear_phosphorylated_erk",
"label": "nuclear phosphorylated ERK",
"maps_to": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.nuclear_phosphorylated_erk",
"description": "nuclear phosphorylated ERK. Maps to SBML symbol `species_1` and is emitted in native SBML units."
},
{
"name": "pp_erk_n",
"label": "Pp ERK N",
"maps_to": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.pp_erk_n",
"description": "Pp ERK N. Maps to SBML symbol `species_2` and is emitted in native SBML units."
},
{
"name": "cytosolic_phosphorylated_erk",
"label": "cytosolic phosphorylated ERK",
"maps_to": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.cytosolic_phosphorylated_erk",
"description": "cytosolic phosphorylated ERK. Maps to SBML symbol `species_6` and is emitted in native SBML units."
},
{
"name": "state",
"label": "Observable state",
"maps_to": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.state"
},
{
"name": "summary",
"label": "Simulation summary",
"maps_to": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.summary"
},
{
"name": "species_labels",
"label": "Observable labels",
"maps_to": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.species_labels"
}
]
},
"tags": [
"signaling",
"systems",
"systems-biology",
"sbml",
"faithful",
"biomodels_ebi",
"mapk",
"ras-erk"
],
"title": "Perrett2014 - GnRH pulse, ERK activity Lab",
"models": [
{
"path": "models/core",
"alias": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model_state"
],
"from": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.state"
},
{
"to": [
"visualisation.signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model_summary"
],
"from": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.summary"
},
{
"to": [
"visualisation.signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model_species_labels"
],
"from": "signaling_sbml_perrett2014_gnrh_pulse_erk_activity_model1509050002_model.species_labels"
}
],
"package": "perrett2014-gnrh-pulse-erk-activity",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Clean Biosimulant lab for MAPK/ERK receptor signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageperrett2014-gnrh-pulse-erk-activity
Created2026-05-16
Updated2026-06-13
signalingsystemssystems-biologysbmlfaithfulbiomodels_ebimapkras-erkvisualisationother