Kawka2014 - Revealing the role of SGK1 in the dynamics of medulloblastoma using a mathematical model Lab
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Clean Biosimulant lab for developmental and growth-control signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_sgk1_t",
"label": "Initial SGK1 T",
"maps_to": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.initial_sgk1_t",
"description": "Initial level of SGK1 T. Maps to SBML symbol `SGK1_t`; exposed as a traceable initial-condition perturbation."
}
],
"outputs": [
{
"name": "sgk1_t",
"label": "SGK1 T",
"maps_to": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.sgk1_t",
"description": "SGK1 T. Maps to SBML symbol `SGK1_t` and is emitted in native SBML units."
},
{
"name": "sgk1_p",
"label": "SGK1 P",
"maps_to": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.sgk1_p",
"description": "SGK1 P. Maps to SBML symbol `SGK1_p` and is emitted in native SBML units."
},
{
"name": "source_defined_myc_t_state",
"label": "source-defined MYC_T state",
"maps_to": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.source_defined_myc_t_state",
"description": "source-defined MYC_T state. Maps to SBML symbol `MYC_t` and is emitted in native SBML units."
},
{
"name": "state",
"label": "Observable state",
"maps_to": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.state"
},
{
"name": "summary",
"label": "Simulation summary",
"maps_to": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.summary"
},
{
"name": "species_labels",
"label": "Observable labels",
"maps_to": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.species_labels"
}
]
},
"tags": [
"signaling",
"systems",
"systems-biology",
"sbml",
"faithful",
"biomodels_ebi",
"wnt"
],
"title": "Kawka2014 - Revealing the role of SGK1 in the dynamics of medulloblastoma using a mathematical model Lab",
"models": [
{
"path": "models/core",
"alias": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model_state"
],
"from": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.state"
},
{
"to": [
"visualisation.signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model_summary"
],
"from": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.summary"
},
{
"to": [
"visualisation.signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model_species_labels"
],
"from": "signaling_sbml_kawka2014_revealing_the_role_of_sgk1_in_the_dyna_model1912090002_model.species_labels"
}
],
"package": "kawka2014-revealing-the-role-of-sgk1-in-the-dyna",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Clean Biosimulant lab for developmental and growth-control signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagekawka2014-revealing-the-role-of-sgk1-in-the-dyna
Created2026-05-16
Updated2026-06-13
signalingsystemssystems-biologysbmlfaithfulbiomodels_ebiwntvisualisationother