Mijailovich2000 - Calcium Cross Bridge Phosphorylation Contraction Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_phosphorylated_myosin",
        "label": "Initial Phosphorylated Myosin",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.initial_phosphorylated_myosin",
        "description": "Initial value for Phosphorylated Myosin. Maps to source symbol `Mp`. Units: dimensionless. Naming evidence: source metadata names `Mp` as `phosphorylated myosin`.",
        "accepted_units": [
          "dimensionless"
        ]
      },
      {
        "name": "initial_phosphorylated_actin_myosin_complex",
        "label": "Initial Phosphorylated Actin Myosin Complex",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.initial_phosphorylated_actin_myosin_complex",
        "description": "Initial value for Phosphorylated Actin Myosin Complex. Maps to source symbol `AMp`. Units: dimensionless. Naming evidence: source metadata names `AMp` as `phosphorylated actin-myosin complex`.",
        "accepted_units": [
          "dimensionless"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.variable_labels"
      },
      {
        "name": "phosphorylated_myosin",
        "label": "Phosphorylated Myosin",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.phosphorylated_myosin",
        "description": "Phosphorylated Myosin. Maps to source symbol `Mp`. Units: dimensionless. Naming evidence: source metadata names `Mp` as `phosphorylated myosin`."
      },
      {
        "name": "phosphorylated_actin_myosin_complex",
        "label": "Phosphorylated Actin Myosin Complex",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.phosphorylated_actin_myosin_complex",
        "description": "Phosphorylated Actin Myosin Complex. Maps to source symbol `AMp`. Units: dimensionless. Naming evidence: source metadata names `AMp` as `phosphorylated actin-myosin complex`."
      },
      {
        "name": "actin_myosin_complex",
        "label": "Actin Myosin Complex",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.actin_myosin_complex",
        "description": "Actin Myosin Complex. Maps to source symbol `AM`. Units: dimensionless. Naming evidence: source metadata names `AM` as `actin-myosin complex`."
      },
      {
        "name": "myosin",
        "label": "Myosin",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.myosin",
        "description": "Myosin. Maps to source symbol `M`. Units: dimensionless. Naming evidence: source metadata names `M` as `myosin`."
      },
      {
        "name": "fp1",
        "label": "Fp1",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.fp1",
        "description": "Fp1. Maps to source symbol `fp1`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "gp1",
        "label": "Gp1",
        "maps_to": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.gp1",
        "description": "Gp1. Maps to source symbol `gp1`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Mijailovich2000 - Calcium Cross Bridge Phosphorylation Contraction Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model",
      "parameters": {
        "model_path": "data/mijailovich_butler_fredburg_2000.cellml",
        "integration_step": 0.01
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model_state"
      ],
      "from": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model_summary"
      ],
      "from": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model_trajectory"
      ],
      "from": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model_variable_labels"
      ],
      "from": "physiology_cellml_mijailovich_butler_fredburg_2000_mijailovichbutlerfredburg2000_model.variable_labels"
    }
  ],
  "package": "mijailovich2000-calcium-cross-bridge-phosphorylation-contraction",
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "version": "1.0.1",
  "description": "Source-faithful physiology lab for Mijailovich, Butler, Fredburg, 2000. Public controls and outputs are mapped to real source symbols for calcium handling.",
  "schema_version": "2.0"
}