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Qosa2014 - Mechanistic modeling thatdescribes Aβ clearance across BBB Qosa2014 - Mechanistic modeling thatdescribes Aβ clearance across BBB. It can be used to explore dose-response dynamics and compare treatment scenarios across conditions.
Manifest
{
"io": {
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{
"name": "initial_cellular_amyloid_beta_hcmec_d3",
"label": "Initial Cellular Amyloid Beta Hcmec D3",
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{
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"label": "Initial Cellular Amyloid Beta Bend3",
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{
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{
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{
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},
{
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{
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{
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"maps_to": "pharmacology_sbml_qosa2014_mechanistic_modeling_that_describes_amy_model1409240002_model.cellular_amyloid_beta_hcmec_d3"
},
{
"name": "degraded_amyloid_beta_hcmec_d3",
"label": "Degraded Amyloid Beta Hcmec D3",
"maps_to": "pharmacology_sbml_qosa2014_mechanistic_modeling_that_describes_amy_model1409240002_model.degraded_amyloid_beta_hcmec_d3"
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{
"name": "cellular_amyloid_beta_bend3",
"label": "Cellular Amyloid Beta Bend3",
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},
{
"name": "degraded_amyloid_beta_bend3",
"label": "Degraded Amyloid Beta Bend3",
"maps_to": "pharmacology_sbml_qosa2014_mechanistic_modeling_that_describes_amy_model1409240002_model.degraded_amyloid_beta_bend3"
},
{
"name": "media_amyloid_beta_hcmec_d3",
"label": "Media Amyloid Beta Hcmec D3",
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},
{
"name": "media_amyloid_beta_bend3",
"label": "Media Amyloid Beta Bend3",
"maps_to": "pharmacology_sbml_qosa2014_mechanistic_modeling_that_describes_amy_model1409240002_model.media_amyloid_beta_bend3"
}
]
},
"tags": [
"pharmacology",
"neuroscience",
"pbpk",
"physiology",
"blood-brain-barrier",
"sbml",
"tellurium",
"faithful",
"biomodels_ebi"
],
"title": "Qosa2014 - Mechanistic modeling that describes amyloid-Beta clearance across BBB Lab",
"models": [
{
"path": "models/core",
"alias": "pharmacology_sbml_qosa2014_mechanistic_modeling_that_describes_amy_model1409240002_model",
"parameters": {
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"integration_step": 0.1
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
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}
],
"package": "qosa2014-amyloid-beta-bbb-clearance",
"runtime": {
"duration": 24,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Qosa2014 - Mechanistic modeling thatdescribes Aβ clearance across BBB Qosa2014 - Mechanistic modeling thatdescribes Aβ clearance across BBB. It can be used to explore dose-response dynamics and compare treatment scenarios across conditions.",
"schema_version": "2.0"
}Runtime
Duration24
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageqosa2014-amyloid-beta-bbb-clearance
Created2026-05-16
Updated2026-06-13
pharmacologyneurosciencepbpkphysiologyblood-brain-barriersbmltelluriumfaithfulbiomodels_ebivisualisationother