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Clean Biosimulant lab for systems signaling model: Brummel-Ziedins2012 - Contribution of the PC pathway to thrombin generation. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_source_defined_tf_state",
"label": "Initial source-defined TF state",
"maps_to": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.initial_source_defined_tf_state",
"description": "Initial level of source-defined TF state. Maps to SBML symbol `TF`; exposed as a traceable initial-condition perturbation."
}
],
"outputs": [
{
"name": "viii_ica1",
"label": "VIII Ica1",
"maps_to": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.viii_ica1",
"description": "VIII Ica1. Maps to SBML symbol `VIII_Ica1` and is emitted in native SBML units."
},
{
"name": "source_defined_lca1_state",
"label": "source-defined LCA1 state",
"maps_to": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.source_defined_lca1_state",
"description": "source-defined LCA1 state. Maps to SBML symbol `LCA1` and is emitted in native SBML units."
},
{
"name": "apc_lca1",
"label": "APC LCA1",
"maps_to": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.apc_lca1",
"description": "APC LCA1. Maps to SBML symbol `APC_LCA1` and is emitted in native SBML units."
},
{
"name": "state",
"label": "Observable state",
"maps_to": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.state"
},
{
"name": "summary",
"label": "Simulation summary",
"maps_to": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.summary"
},
{
"name": "species_labels",
"label": "Observable labels",
"maps_to": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.species_labels"
}
]
},
"tags": [
"signaling",
"systems",
"systems-biology",
"sbml",
"faithful",
"biomodels_ebi",
"coagulation",
"physiology"
],
"title": "Brummel-Ziedins2012 - Contribution of the PC pathway to thrombin generation Lab",
"models": [
{
"path": "models/core",
"alias": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model_state"
],
"from": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.state"
},
{
"to": [
"visualisation.signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model_summary"
],
"from": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.summary"
},
{
"to": [
"visualisation.signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model_species_labels"
],
"from": "signaling_sbml_brummel_ziedins2012_contribution_of_the_pc_pathw_model1807180002_model.species_labels"
}
],
"package": "brummel-ziedins2012-contribution-of-the-pc-pathw",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Clean Biosimulant lab for systems signaling model: Brummel-Ziedins2012 - Contribution of the PC pathway to thrombin generation. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagebrummel-ziedins2012-contribution-of-the-pc-pathw
Created2026-05-16
Updated2026-06-13
signalingsystemssystems-biologysbmlfaithfulbiomodels_ebicoagulationphysiologyvisualisationother