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The paper describes a model of re-polarisation of M2 and M1 macrophages and its role on cancer outcomes. Created by COPASI 4.25 (Build 207) This model is described in the article: The re-polarisation.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_unresolved_tumor_observable_1",
"label": "Initial Unresolved Tumor Observable 1",
"units": "native source value",
"default": 1000,
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_1",
"description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `Tn`."
},
{
"name": "initial_unresolved_tumor_observable_2",
"label": "Initial Unresolved Tumor Observable 2",
"units": "native source value",
"default": 1000000,
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_2",
"description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `Ts`."
},
{
"name": "initial_unresolved_tumor_observable_3",
"label": "Initial Unresolved Tumor Observable 3",
"units": "native source value",
"default": 100,
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_3",
"description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `M1`."
},
{
"name": "initial_unresolved_tumor_observable_4",
"label": "Initial Unresolved Tumor Observable 4",
"units": "native source value",
"default": 100,
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_4",
"description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `M2`."
},
{
"name": "initial_unresolved_tumor_observable_5",
"label": "Initial Unresolved Tumor Observable 5",
"units": "native source value",
"default": 0,
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_5",
"description": "Initial Unresolved Tumor Observable 5. Sets the initial value of bundled SBML species `Th1`."
}
],
"outputs": [
{
"name": "unresolved_tumor_observable_1",
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_1"
},
{
"name": "unresolved_tumor_observable_2",
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_2"
},
{
"name": "unresolved_tumor_observable_3",
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_3"
},
{
"name": "unresolved_tumor_observable_4",
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_4"
},
{
"name": "unresolved_tumor_observable_5",
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_5"
},
{
"name": "state",
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.species_labels"
}
]
},
"title": "den Breems2015 - macrophage in cancer Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model_state"
],
"from": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.state"
},
{
"to": [
"visualisation.immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model_summary"
],
"from": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model_species_labels"
],
"from": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.species_labels"
}
],
"package": "den-breems2015-macrophage-in-cancer",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.1",
"description": "The paper describes a model of re-polarisation of M2 and M1 macrophages and its role on cancer outcomes. Created by COPASI 4.25 (Build 207) This model is described in the article: The re-polarisation.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageden-breems2015-macrophage-in-cancer
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother