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Heldt2012 - Influenza Virus Replication The model describes the life cycle of influenza A virus in a mammalian cell including the following steps: attachment of parental virions to the cell membrane,. It can be used to explore systemsbiology heldt2012 influenza virus replication BioModels0000000463 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_total_v_rna_of_a_segment",
"label": "Initial Total V RNA Of A Segment",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.initial_total_v_rna_of_a_segment",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_39`."
},
{
"name": "initial_total_v_rna",
"label": "Initial Total V RNA",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.initial_total_v_rna",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_38`."
},
{
"name": "initial_total_c_rna_of_a_segment",
"label": "Initial Total C RNA Of A Segment",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.initial_total_c_rna_of_a_segment",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_37`."
},
{
"name": "initial_total_c_rna",
"label": "Initial Total C RNA",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.initial_total_c_rna",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_36`."
},
{
"name": "initial_model_state_blo",
"label": "Initial Model State Blo",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.initial_model_state_blo",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_4`."
},
{
"name": "initial_model_state_bhi",
"label": "Initial Model State Bhi",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.initial_model_state_bhi",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `species_1`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.species_labels"
},
{
"name": "total_v_rna_of_a_segment",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.total_v_rna_of_a_segment"
},
{
"name": "total_v_rna",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.total_v_rna"
},
{
"name": "total_c_rna_of_a_segment",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.total_c_rna_of_a_segment"
},
{
"name": "total_c_rna",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.total_c_rna"
},
{
"name": "blo",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.blo"
},
{
"name": "bhi",
"maps_to": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.bhi"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Heldt2012 Influenza Virus Replication Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model_state"
],
"from": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model_summary"
],
"from": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model_species_labels"
],
"from": "systemsbiology_sbml_heldt2012_influenza_virus_replication_biomd0000000463_model.species_labels"
}
],
"package": "heldt2012-influenza-virus-replication",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Heldt2012 - Influenza Virus Replication The model describes the life cycle of influenza A virus in a mammalian cell including the following steps: attachment of parental virions to the cell membrane,. It can be used to explore systemsbiology heldt2012 influenza virus replication BioModels0000000463 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageheldt2012-influenza-virus-replication
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother