Smith2010 - Response of FOXO Transcription Factors to Post-Translational Modifications Made by Ageing-Related Signalling Pathways Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cytoplasm_foxo1_total",
        "label": "Initial Cytoplasm Foxo1 Total",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.initial_cytoplasm_foxo1_total",
        "description": "Initial level of Cytoplasm Foxo1 Total. Maps to SBML symbol `cytoplasm_Foxo1_tot`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_degr_foxo1",
        "label": "Initial Degr Foxo1",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.initial_degr_foxo1",
        "description": "Initial level of Degr Foxo1. Maps to SBML symbol `degr_Foxo1`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_dnabound_foxo1_total",
        "label": "Initial Dnabound Foxo1 Total",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.initial_dnabound_foxo1_total",
        "description": "Initial level of Dnabound Foxo1 Total. Maps to SBML symbol `dnabound_Foxo1_tot`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "cytoplasm_foxo1_unpolyubiquitinated_unphosphorylated",
        "label": "Cytoplasm Foxo1 Unpolyubiquitinated Unphosphorylated",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.cytoplasm_foxo1_unpolyubiquitinated_unphosphorylated",
        "description": "Cytoplasm Foxo1 Unpolyubiquitinated Unphosphorylated. Maps to SBML symbol `cytoplasm_Foxo1_Pa0_pUb0` and is emitted in native SBML units."
      },
      {
        "name": "nucleus_foxo1_unpolyubiquitinated_unphosphorylated",
        "label": "Nucleus Foxo1 Unpolyubiquitinated Unphosphorylated",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.nucleus_foxo1_unpolyubiquitinated_unphosphorylated",
        "description": "Nucleus Foxo1 Unpolyubiquitinated Unphosphorylated. Maps to SBML symbol `nucleus_Foxo1_Pa0_pUb0` and is emitted in native SBML units."
      },
      {
        "name": "dnabound_foxo1_unpolyubiquitinated_unphosphorylated",
        "label": "Dnabound Foxo1 Unpolyubiquitinated Unphosphorylated",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.dnabound_foxo1_unpolyubiquitinated_unphosphorylated",
        "description": "Dnabound Foxo1 Unpolyubiquitinated Unphosphorylated. Maps to SBML symbol `dnabound_Foxo1_Pa0_pUb0` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "cellular-signaling"
  ],
  "title": "Smith2010 - Response of FOXO Transcription Factors to Post-Translational Modifications Made by Ageing-Related Signalling Pathways Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model_state"
      ],
      "from": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model_summary"
      ],
      "from": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model_species_labels"
      ],
      "from": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000705_model.species_labels"
    }
  ],
  "package": "smith2010-response-of-foxo-transcription-factors",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for systems signaling model: Smith2010 - Response of FOXO Transcription Factors to Post-Translational Modifications Made by Ageing-Related Signalling Pathways. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}