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This model describes the interactions between tumor cells and virus particles, with particular reference to virus-induced syncytium formation and ultimately death of tumor cells. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "epsilon_source_parameter",
"label": "Epsilon source parameter",
"units": "native SBML value",
"default": 1.648773,
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.epsilon_source_parameter",
"description": "Epsilon source parameter. Maps to bundled SBML parameter `epsilon`."
},
{
"name": "initial_y_tumor_cell",
"label": "Y Tumor Cell",
"units": "native SBML value",
"default": 126.237,
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.initial_y_tumor_cell",
"description": "Initial Y Tumor Cell. Sets the initial value of bundled SBML symbol `y_Tumor_Cell`."
},
{
"name": "initial_x_infected_cell",
"label": "X Infected Cell",
"units": "native SBML value",
"default": 0,
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.initial_x_infected_cell",
"description": "Initial X Infected Cell. Sets the initial value of bundled SBML symbol `x_Infected_Cell`."
},
{
"name": "initial_v_virus",
"label": "V Virus",
"units": "native SBML value",
"default": 2,
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.initial_v_virus",
"description": "Initial V Virus. Sets the initial value of bundled SBML symbol `v_Virus`."
}
],
"outputs": [
{
"name": "y_tumor_cell",
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.y_tumor_cell",
"description": "Y Tumor Cell observable. Maps to SBML symbol `y_Tumor_Cell`."
},
{
"name": "x_infected_cell",
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.x_infected_cell",
"description": "X Infected Cell observable. Maps to SBML symbol `x_Infected_Cell`."
},
{
"name": "v_virus",
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.v_virus",
"description": "V Virus observable. Maps to SBML symbol `v_Virus`."
},
{
"name": "state",
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"drug-response",
"faithful",
"immunotherapy",
"oncology",
"pharmacology",
"physiology",
"sbml",
"systemsbiology",
"tumor-growth",
"virotherapy"
],
"title": "Bajzer2008 - Modeling of cancer virotherapy with recombinant measles viruses Lab",
"models": [
{
"path": "models/core",
"alias": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model_state"
],
"from": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.state"
},
{
"to": [
"visualisation.oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model_summary"
],
"from": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model_species_labels"
],
"from": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.species_labels"
}
],
"package": "bajzer2008-modeling-of-cancer-virotherapy-with-recombin-62d71656",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This model describes the interactions between tumor cells and virus particles, with particular reference to virus-induced syncytium formation and ultimately death of tumor cells. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagebajzer2008-modeling-of-cancer-virotherapy-with-recombin-62d71656
Created2026-05-16
Updated2026-06-13
biomodels_ebicurateddrug-responsefaithfulimmunotherapyoncologypharmacologyphysiologysbmlsystemsbiologytumor-growthvirotherapyvisualisationother