vanBeek2007_OxPhos_HeartMuscleCells Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cytosolic_atp",
        "units": "native SBML value",
        "default": 5912.77,
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.initial_cytosolic_atp",
        "description": "Initial condition for cytosolic atp. Maps to bundled SBML symbol `ATP_cyt`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_cytosolic_adp",
        "units": "native SBML value",
        "default": 64,
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.initial_cytosolic_adp",
        "description": "Initial condition for cytosolic adp. Maps to bundled SBML symbol `ADP_cyt`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_mitochondrial_energy_state_3_cytosolic",
        "units": "native SBML value",
        "default": 5000,
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.initial_mitochondrial_energy_state_3_cytosolic",
        "description": "Initial condition for mitochondrial energy state 3 cytosolic. Maps to bundled SBML symbol `PCr_cyt`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_mitochondrial_energy_state_4_cytosolic",
        "units": "native SBML value",
        "default": 10500,
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.initial_mitochondrial_energy_state_4_cytosolic",
        "description": "Initial condition for mitochondrial energy state 4 cytosolic. Maps to bundled SBML symbol `Cr_cyt`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_mitochondrial_energy_state_5_cytosolic",
        "units": "native SBML value",
        "default": 913,
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.initial_mitochondrial_energy_state_5_cytosolic",
        "description": "Initial condition for mitochondrial energy state 5 cytosolic. Maps to bundled SBML symbol `Pi_cyt`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "cytosolic_atp",
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.cytosolic_atp"
      },
      {
        "name": "cytosolic_adp",
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.cytosolic_adp"
      },
      {
        "name": "mitochondrial_energy_state_3_cytosolic",
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.mitochondrial_energy_state_3_cytosolic"
      },
      {
        "name": "mitochondrial_energy_state_4_cytosolic",
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.mitochondrial_energy_state_4_cytosolic"
      },
      {
        "name": "mitochondrial_energy_state_5_cytosolic",
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.mitochondrial_energy_state_5_cytosolic"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.observable_labels"
      }
    ]
  },
  "title": "vanBeek2007_OxPhos_HeartMuscleCells Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model",
      "parameters": {
        "model_path": "data/MODEL1006230027.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model_observable_values"
      ],
      "from": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model_run_summary"
      ],
      "from": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model_observable_labels"
      ],
      "from": "metabolism_sbml_vanbeek2007_oxphos_heartmusclecells_model1006230027_model.observable_labels"
    }
  ],
  "package": "vanbeek2007-oxphos-heartmusclecells",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This a model from the article: Adenine nucleotide-creatine-phosphate module in myocardial metabolic systemexplains fast phase of dynamic regulation of oxidative phosphorylation. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.",
  "schema_version": "2.0"
}