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The Mothes2020_NFkB_A20_signaling model is based on our previous model published in Murakawa et al., Nat Commun, 2015 (doi: 10.1038/ncomms8367). It can be used to explore systemsbiology mothes2020 nfkb a20 signaling model2307110001 dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "stimulus",
"label": "Stimulus",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.stimulus",
"description": "Source parameter exposed because its SBML label indicates a boundary, stimulus, dose, ligand, protocol, substrate, or environmental control. Maps to SBML symbol `stimulus`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.species_labels"
},
{
"name": "a20_mrna",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.a20_mrna"
},
{
"name": "ik_ba_mrna",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.ik_ba_mrna"
},
{
"name": "n_fk_b_ik_ba",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.n_fk_b_ik_ba"
},
{
"name": "ik_ba",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.ik_ba"
},
{
"name": "a20",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.a20"
},
{
"name": "ikk_active",
"maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.ikk_active"
}
]
},
"tags": [
"signaling",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Mothes2020 Nfkb A20 Signaling Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model_state"
],
"from": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model_summary"
],
"from": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model_species_labels"
],
"from": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.species_labels"
}
],
"package": "mothes2020-nfkb-a20-signaling",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "The Mothes2020_NFkB_A20_signaling model is based on our previous model published in Murakawa et al., Nat Commun, 2015 (doi: 10.1038/ncomms8367). It can be used to explore systemsbiology mothes2020 nfkb a20 signaling model2307110001 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagemothes2020-nfkb-a20-signaling
Created2026-05-17
Updated2026-06-13
signalingsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother