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Created by The MathWorks, Inc. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_unresolved_infection_observable_1",
"label": "Initial Unresolved Infection Observable 1",
"units": "MWBUILTINPREFIX_nano_MWBUILTINUNIT_mole",
"default": 0.9,
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.initial_unresolved_infection_observable_1",
"description": "Initial Unresolved Infection Observable 1. Sets the initial value of bundled SBML species `mw68f058f9_e632_469e_a51e_b0641d5ac5f1`."
},
{
"name": "initial_unresolved_infection_observable_2",
"label": "Initial Unresolved Infection Observable 2",
"units": "MWBUILTINPREFIX_nano_MWBUILTINUNIT_mole",
"default": 0.38,
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.initial_unresolved_infection_observable_2",
"description": "Initial Unresolved Infection Observable 2. Sets the initial value of bundled SBML species `mw589e86be_36cb_41e1_bccf_93824d618644`."
},
{
"name": "initial_unresolved_infection_observable_3",
"label": "Initial Unresolved Infection Observable 3",
"units": "MWBUILTINPREFIX_nano_MWBUILTINUNIT_mole",
"default": 0.56,
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.initial_unresolved_infection_observable_3",
"description": "Initial Unresolved Infection Observable 3. Sets the initial value of bundled SBML species `mw389efde0_d330_42e0_b68c_cb0cfbf8a3c9`."
},
{
"name": "initial_irak4_irak1_complex",
"label": "Initial Irak4 Irak1 Complex",
"units": "MWBUILTINPREFIX_nano_MWBUILTINUNIT_mole",
"default": 0.6,
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.initial_irak4_irak1_complex",
"description": "Initial Irak4 Irak1 Complex. Sets the initial value of bundled SBML species `mw86470798_a991_412f_a9bb_574001df871d`."
},
{
"name": "initial_tumor_necrosis_factor",
"label": "Initial Tumor Necrosis Factor",
"units": "MWBUILTINPREFIX_nano_MWBUILTINUNIT_mole",
"default": 0.8,
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.initial_tumor_necrosis_factor",
"description": "Initial Tumor Necrosis Factor. Sets the initial value of bundled SBML species `mw4535fcdd_0cf2_4ee4_8d52_eadd3c4fec92`."
}
],
"outputs": [
{
"name": "unresolved_infection_observable_1",
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.unresolved_infection_observable_1"
},
{
"name": "unresolved_infection_observable_2",
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.unresolved_infection_observable_2"
},
{
"name": "unresolved_infection_observable_3",
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.unresolved_infection_observable_3"
},
{
"name": "irak4_irak1_complex",
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.irak4_irak1_complex"
},
{
"name": "tumor_necrosis_factor",
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.tumor_necrosis_factor"
},
{
"name": "state",
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.species_labels"
}
]
},
"title": "Mol2013 - Leishmania macrophage signaling network Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model_state"
],
"from": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.state"
},
{
"to": [
"visualisation.immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model_summary"
],
"from": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model_species_labels"
],
"from": "immunology_sbml_mol2013_leishmania_macrophage_signaling_network_model1203220000_model.species_labels"
}
],
"package": "mol2013-leishmania-macrophage-signaling-network",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Created by The MathWorks, Inc. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagemol2013-leishmania-macrophage-signaling-network
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother