Chedere2022 - NAD Biosynthesis in Human Liver Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_l_formyl_kyneurenine",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.initial_l_formyl_kyneurenine",
        "description": "Initial condition for l formyl kyneurenine. Maps to bundled SBML symbol `L_formyl_kyn`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_hydroxykynurenine",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.initial_hydroxykynurenine",
        "description": "Initial condition for hydroxykynurenine. Maps to bundled SBML symbol `Hydroxyurenine`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_nad_metabolism_state_3",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.initial_nad_metabolism_state_3",
        "description": "Initial condition for nad metabolism state 3. Maps to bundled SBML symbol `Hydroxyanthranilate`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_nad_metabolism_state_4",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.initial_nad_metabolism_state_4",
        "description": "Initial condition for nad metabolism state 4. Maps to bundled SBML symbol `Quinolinate`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_nad_metabolism_state_5",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.initial_nad_metabolism_state_5",
        "description": "Initial condition for nad metabolism state 5. Maps to bundled SBML symbol `NaMN`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "l_formyl_kyneurenine",
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.l_formyl_kyneurenine"
      },
      {
        "name": "hydroxykynurenine",
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.hydroxykynurenine"
      },
      {
        "name": "nad_metabolism_state_3",
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.nad_metabolism_state_3"
      },
      {
        "name": "nad_metabolism_state_4",
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.nad_metabolism_state_4"
      },
      {
        "name": "nad_metabolism_state_5",
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.nad_metabolism_state_5"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.observable_labels"
      }
    ]
  },
  "title": "Chedere2022 - NAD Biosynthesis in Human Liver Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model",
      "parameters": {
        "model_path": "data/MODEL2205250001.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model_observable_values"
      ],
      "from": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model_run_summary"
      ],
      "from": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model_observable_labels"
      ],
      "from": "metabolism_sbml_chedere2022_nad_biosynthesis_in_human_liver_model2205250001_model.observable_labels"
    }
  ],
  "package": "chedere2022-nad-biosynthesis-in-human-liver",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This SBML (L2V4) file is a well-annotated ODE-based model created to capture NAD biosynthesis in the human liver. This model contains 26 reactions with 29 genes, 31 metabolites and 138 parameters.",
  "schema_version": "2.0"
}