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Blood coagulation model using an updated Hockin2002 model. New reactions for factor X and V activation by IXa and mIIa respectively (reactions R28 and R29, parameters k43 and k44).
Manifest
{
"io": {
"inputs": [
{
"name": "initial_m_i_ia_atiii",
"label": "Initial M I Ia Atiii",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_m_i_ia_atiii",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mIIa_ATIII`."
},
{
"name": "initial_m_i_ia",
"label": "Initial M I Ia",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_m_i_ia",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mIIa`."
},
{
"name": "initial_xa_va_ii",
"label": "Initial Xa Va Ii",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_xa_va_ii",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_Va_II`."
},
{
"name": "initial_xa_va",
"label": "Initial Xa Va",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_xa_va",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_Va`."
},
{
"name": "initial_xa_tfpi",
"label": "Initial Xa Tfpi",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_xa_tfpi",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_TFPI`."
},
{
"name": "initial_xa_atiii",
"label": "Initial Xa Atiii",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_xa_atiii",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_ATIII`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.species_labels"
},
{
"name": "m_i_ia_atiii",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.m_i_ia_atiii"
},
{
"name": "m_i_ia",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.m_i_ia"
},
{
"name": "xa_va_ii",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.xa_va_ii"
},
{
"name": "xa_va",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.xa_va"
},
{
"name": "xa_tfpi",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.xa_tfpi"
},
{
"name": "xa_atiii",
"maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.xa_atiii"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Mitrophanov2013 Simulation Of Hockin Blood Coagulation Model Under Reduced Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model_state"
],
"from": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model_summary"
],
"from": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model_species_labels"
],
"from": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.species_labels"
}
],
"package": "mitrophanov2013-simulation-of-hockin-blood-coagulation-aa569237",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Blood coagulation model using an updated Hockin2002 model. New reactions for factor X and V activation by IXa and mIIa respectively (reactions R28 and R29, parameters k43 and k44).",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagemitrophanov2013-simulation-of-hockin-blood-coagulation-aa569237
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother