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This is a mathematical model of heat shock protein synthesis induced by an external temperature stimulus. The model consists of a system of nine nonlinear ordinary differential equations describing th.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_hsp70_hsf",
"label": "Initial Hsp70 Hsf",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.initial_hsp70_hsf",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Hsp70_HSF`."
},
{
"name": "initial_mrna",
"label": "Initial MRNA",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.initial_mrna",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mRNA`."
},
{
"name": "initial_hsf_3_hse",
"label": "Initial Hsf 3 Hse",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.initial_hsf_3_hse",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `HSF_3_HSE`."
},
{
"name": "initial_hsf_3",
"label": "Initial Hsf 3",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.initial_hsf_3",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `HSF_3`."
},
{
"name": "initial_hsp70_s",
"label": "Initial Hsp70 S",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.initial_hsp70_s",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Hsp70_S`."
},
{
"name": "initial_model_state_hse",
"label": "Initial Model State Hse",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.initial_model_state_hse",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `HSE`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.species_labels"
},
{
"name": "hsp70_hsf",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.hsp70_hsf"
},
{
"name": "mrna",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.mrna"
},
{
"name": "hsf_3_hse",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.hsf_3_hse"
},
{
"name": "hsf_3",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.hsf_3"
},
{
"name": "hsp70_s",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.hsp70_s"
},
{
"name": "hse",
"maps_to": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.hse"
}
]
},
"tags": [
"generegulation",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Szymanska2009 Mathematical Modeling Of Heat Shock Protein Synthesis In R Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model_state"
],
"from": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model_summary"
],
"from": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model_species_labels"
],
"from": "systemsbiology_sbml_szymanska2009_mathematical_modeling_of_heat_shoc_biomd0000000896_model.species_labels"
}
],
"package": "szymanska2009-mathematical-modeling-of-heat-shock-prote-87e106dc",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This is a mathematical model of heat shock protein synthesis induced by an external temperature stimulus. The model consists of a system of nine nonlinear ordinary differential equations describing th.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageszymanska2009-mathematical-modeling-of-heat-shock-prote-87e106dc
Created2026-05-17
Updated2026-06-13
generegulationsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother