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Proctor2012 - Amyloid-beta aggregation This model supports the current thinking that levels of dimers are important in initiating the aggregation process. This model is described in the article: Aggre.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_neprilysin",
"label": "Initial Neprilysin",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.initial_neprilysin",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Nep`."
},
{
"name": "initial_abeta_plaque",
"label": "Initial Abeta Plaque",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.initial_abeta_plaque",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `AbP`."
},
{
"name": "initial_abeta_monomer",
"label": "Initial Abeta Monomer",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.initial_abeta_monomer",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Abeta`."
},
{
"name": "initial_abeta_dimer",
"label": "Initial Abeta Dimer",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.initial_abeta_dimer",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `AbDim`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.species_labels"
},
{
"name": "neprilysin",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.neprilysin"
},
{
"name": "abeta_plaque",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.abeta_plaque"
},
{
"name": "abeta_monomer",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.abeta_monomer"
},
{
"name": "abeta_dimer",
"maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.abeta_dimer"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Proctor2012 Role Of Amyloid Beta Dimers In Aggregation Formation Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model_state"
],
"from": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model_summary"
],
"from": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model_species_labels"
],
"from": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.species_labels"
}
],
"package": "proctor2012-role-of-amyloid-beta-dimers-in-aggregation-formation",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.1",
"description": "Proctor2012 - Amyloid-beta aggregation This model supports the current thinking that levels of dimers are important in initiating the aggregation process. This model is described in the article: Aggre.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageproctor2012-role-of-amyloid-beta-dimers-in-aggregation-formation
Created2026-05-17
Updated2026-06-13
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother