Vempati2007 - Biochemical Matrix Metalloproteinase 9 Activation Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_inactivated_mmp9_timp1",
        "label": "Initial Inactivated Mmp9 Timp1",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.initial_inactivated_mmp9_timp1",
        "description": "Initial value for Inactivated Mmp9 Timp1. Maps to source symbol `M9_T1_star`. Units: molar. Naming evidence: source metadata names `M9_T1_star` as `inactivated MMP9-TIMP1`.",
        "accepted_units": [
          "molar"
        ]
      },
      {
        "name": "initial_matrix_metalloproteinase_3",
        "label": "Initial Matrix Metalloproteinase 3",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.initial_matrix_metalloproteinase_3",
        "description": "Initial value for Matrix Metalloproteinase 3. Maps to source symbol `M3`. Units: molar. Naming evidence: source metadata names `M3` as `matrix metalloproteinase-3`.",
        "accepted_units": [
          "molar"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.variable_labels"
      },
      {
        "name": "matrix_metalloproteinase_3",
        "label": "Matrix Metalloproteinase 3",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.matrix_metalloproteinase_3",
        "description": "Matrix Metalloproteinase 3. Maps to source symbol `M3`. Units: molar. Naming evidence: source metadata names `M3` as `matrix metalloproteinase-3`."
      },
      {
        "name": "matrix_metalloproteinase_9",
        "label": "Matrix Metalloproteinase 9",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.matrix_metalloproteinase_9",
        "description": "Matrix Metalloproteinase 9. Maps to source symbol `M9`. Units: molar. Naming evidence: source metadata names `M9` as `matrix metalloproteinase-9`."
      },
      {
        "name": "timp1",
        "label": "Timp1",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.timp1",
        "description": "Timp1. Maps to source symbol `T1`. Units: molar. Naming evidence: source metadata names `T1` as `TIMP1`."
      },
      {
        "name": "trypsin",
        "label": "Trypsin",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.trypsin",
        "description": "Trypsin. Maps to source symbol `Tr`. Units: molar. Naming evidence: source metadata names `Tr` as `trypsin`."
      },
      {
        "name": "matrix_metalloproteinase_3_promatrix_metalloproteinase_9_complex",
        "label": "Matrix Metalloproteinase 3 Promatrix Metalloproteinase 9 Complex",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.matrix_metalloproteinase_3_promatrix_metalloproteinase_9_complex",
        "description": "Matrix Metalloproteinase 3 Promatrix Metalloproteinase 9 Complex. Maps to source symbol `M3_pM9`. Units: molar. Naming evidence: source metadata names `M3_pM9` as `matrix metalloproteinase-3-promatrix metalloproteinase-9 complex`."
      },
      {
        "name": "promatrix_metalloproteinase_9",
        "label": "Promatrix Metalloproteinase 9",
        "maps_to": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.promatrix_metalloproteinase_9",
        "description": "Promatrix Metalloproteinase 9. Maps to source symbol `pM9`. Units: molar. Naming evidence: source metadata names `pM9` as `promatrix metalloproteinase-9`."
      }
    ]
  },
  "title": "Vempati2007 - Biochemical Matrix Metalloproteinase 9 Activation Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model",
      "parameters": {
        "model_path": "data/vempati_karagiannis_popel_2007.cellml",
        "integration_step": 0.01
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model_state"
      ],
      "from": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model_summary"
      ],
      "from": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model_trajectory"
      ],
      "from": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model_variable_labels"
      ],
      "from": "physiology_cellml_vempati_karagiannis_popel_2007_vempatikaragiannispopel2007_model.variable_labels"
    }
  ],
  "package": "vempati2007-biochemical-matrix-metalloproteinase-9-activation",
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "version": "1.0.0",
  "description": "Source-faithful physiology lab for Vempati, Karagiannis, Popel, 2007. Public controls and outputs are mapped to real source symbols for source-model physiology.",
  "schema_version": "2.0"
}