Boer1986 - Interactions between Macrophages and T-lymphocytes: Tumor Sneaking Through Intrinsic to Helper T cell Dynamics Lab

{
  "io": {
    "inputs": [
      {
        "name": "kill_source_parameter",
        "label": "KILL source parameter",
        "units": "native SBML value",
        "default": 10,
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.kill_source_parameter",
        "description": "KILL source parameter. Maps to bundled SBML parameter `KILL`."
      },
      {
        "name": "initial_tumor",
        "label": "TUMOR",
        "units": "native SBML value",
        "default": 1000,
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.initial_tumor",
        "description": "Initial TUMOR. Sets the initial value of bundled SBML symbol `TUMOR`."
      },
      {
        "name": "initial_ctlp",
        "label": "CTLP",
        "units": "native SBML value",
        "default": 1,
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.initial_ctlp",
        "description": "Initial CTLP. Sets the initial value of bundled SBML symbol `CTLP`."
      },
      {
        "name": "initial_htlp",
        "label": "HTLP",
        "units": "native SBML value",
        "default": 15,
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.initial_htlp",
        "description": "Initial HTLP. Sets the initial value of bundled SBML symbol `HTLP`."
      },
      {
        "name": "initial_mph",
        "label": "MPH",
        "units": "native SBML value",
        "default": 3000000,
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.initial_mph",
        "description": "Initial MPH. Sets the initial value of bundled SBML symbol `MPH`."
      },
      {
        "name": "initial_ctl",
        "label": "CTL",
        "units": "native SBML value",
        "default": 3909,
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.initial_ctl",
        "description": "Initial CTL. Sets the initial value of bundled SBML symbol `CTL`."
      }
    ],
    "outputs": [
      {
        "name": "tumor",
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.tumor",
        "description": "TUMOR observable. Maps to SBML symbol `TUMOR`."
      },
      {
        "name": "ctlp",
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.ctlp",
        "description": "CTLP observable. Maps to SBML symbol `CTLP`."
      },
      {
        "name": "htlp",
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.htlp",
        "description": "HTLP observable. Maps to SBML symbol `HTLP`."
      },
      {
        "name": "mph",
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.mph",
        "description": "MPH observable. Maps to SBML symbol `MPH`."
      },
      {
        "name": "ctl",
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.ctl",
        "description": "CTL observable. Maps to SBML symbol `CTL`."
      },
      {
        "name": "htl",
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.htl",
        "description": "HTL observable. Maps to SBML symbol `HTL`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "curated",
    "drug-response",
    "faithful",
    "immunology",
    "immunotherapy",
    "microenvironment",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Boer1986 - Interactions between Macrophages and T-lymphocytes: Tumor Sneaking Through Intrinsic to Helper T cell Dynamics Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model_state"
      ],
      "from": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model_summary"
      ],
      "from": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model_species_labels"
      ],
      "from": "oncology_sbml_boer1986_interactions_between_macrophages_and_t_model1912110001_model.species_labels"
    }
  ],
  "package": "boer1986-interactions-between-macrophages-and-t-lymphoc-98b45fd9",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Interactions between Macrophages and T-lymphocytes: TumorSneaking Through Intrinsic to Helper T cell DynamicsROB J. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
  "schema_version": "2.0"
}