About lab
One published Lab
Build with this Lab. Run it anywhere.
Use the same immutable release locally or through managed cloud execution, with its exact version and provenance preserved.
Preparing exact examples…
This model describes the multistep process that transform a normal cell and its descendants into a malignant tumour by considering three populations: normal, premalignant and cancer cells. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_normalized_normal_cell_n",
"label": "Normalized normal cell n",
"units": "native SBML value",
"default": 0.99999999,
"maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.initial_normalized_normal_cell_n",
"description": "Initial Normalized normal cell n. Sets the initial value of bundled SBML symbol `normalized_normal_cell_n`."
},
{
"name": "initial_normalized_pre_cancer_cell_g",
"label": "Normalized pre cancer cell g",
"units": "native SBML value",
"default": 1e-8,
"maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.initial_normalized_pre_cancer_cell_g",
"description": "Initial Normalized pre cancer cell g. Sets the initial value of bundled SBML symbol `normalized_pre_cancer_cell_g`."
},
{
"name": "initial_normalized_cancer_cell_a",
"label": "Normalized cancer cell a",
"units": "native SBML value",
"default": 0,
"maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.initial_normalized_cancer_cell_a",
"description": "Initial Normalized cancer cell a. Sets the initial value of bundled SBML symbol `normalized_cancer_cell_a`."
}
],
"outputs": [
{
"name": "normalized_normal_cell_n",
"maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.normalized_normal_cell_n",
"description": "Normalized normal cell n observable. Maps to SBML symbol `normalized_normal_cell_n`."
},
{
"name": "normalized_pre_cancer_cell_g",
"maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.normalized_pre_cancer_cell_g",
"description": "Normalized pre cancer cell g observable. Maps to SBML symbol `normalized_pre_cancer_cell_g`."
},
{
"name": "normalized_cancer_cell_a",
"maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.normalized_cancer_cell_a",
"description": "Normalized cancer cell a observable. Maps to SBML symbol `normalized_cancer_cell_a`."
},
{
"name": "state",
"maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"drug-response",
"faithful",
"oncology",
"pharmacology",
"physiology",
"sbml",
"systemsbiology",
"tumor-growth"
],
"title": "Fassoni2019 - Oncogenesis encompassing mutations and genetic instability Lab",
"models": [
{
"path": "models/core",
"alias": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model_state"
],
"from": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.state"
},
{
"to": [
"visualisation.oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model_summary"
],
"from": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model_species_labels"
],
"from": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.species_labels"
}
],
"package": "fassoni2019-oncogenesis-encompassing-mutations-and-gene-c627e928",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This model describes the multistep process that transform a normal cell and its descendants into a malignant tumour by considering three populations: normal, premalignant and cancer cells. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagefassoni2019-oncogenesis-encompassing-mutations-and-gene-c627e928
Created2026-05-16
Updated2026-06-13
biomodels_ebicurateddrug-responsefaithfuloncologypharmacologyphysiologysbmlsystemsbiologytumor-growthvisualisationother