Koschorreck2008_InsulinClearance Lab

{
  "io": {
    "inputs": [
      {
        "name": "liver_insulin_clearance_density",
        "label": "Liver Insulin Clearance Density",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.liver_insulin_clearance_density"
      },
      {
        "name": "initial_free_receptor",
        "label": "Initial Free Receptor",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.initial_free_receptor"
      },
      {
        "name": "initial_insulin_receptor_complex",
        "label": "Initial Insulin Receptor Complex",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.initial_insulin_receptor_complex"
      },
      {
        "name": "initial_internalized_receptor",
        "label": "Initial Internalized Receptor",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.initial_internalized_receptor"
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Tracked source state",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.species_labels"
      },
      {
        "name": "free_receptor",
        "label": "Free Receptor",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.free_receptor"
      },
      {
        "name": "insulin_receptor_complex",
        "label": "Insulin Receptor Complex",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.insulin_receptor_complex"
      },
      {
        "name": "two_insulin_receptor_complex",
        "label": "Two Insulin Receptor Complex",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.two_insulin_receptor_complex"
      },
      {
        "name": "phosphorylated_receptor",
        "label": "Phosphorylated Receptor",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.phosphorylated_receptor"
      },
      {
        "name": "phosphorylated_insulin_receptor_complex",
        "label": "Phosphorylated Insulin Receptor Complex",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.phosphorylated_insulin_receptor_complex"
      },
      {
        "name": "endosomal_receptor",
        "label": "Endosomal Receptor",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.endosomal_receptor"
      },
      {
        "name": "endosomal_insulin_receptor_complex",
        "label": "Endosomal Insulin Receptor Complex",
        "maps_to": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.endosomal_insulin_receptor_complex"
      }
    ]
  },
  "tags": [
    "pharmacology",
    "pharmacokinetics",
    "endocrine",
    "physiology",
    "sbml",
    "tellurium",
    "faithful",
    "biomodels_ebi"
  ],
  "title": "Koschorreck2008_InsulinClearance Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model",
      "parameters": {
        "model_path": "data/BIOMD0000000345.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model_state"
      ],
      "from": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.state"
    },
    {
      "to": [
        "visualisation.pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model_summary"
      ],
      "from": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.summary"
    },
    {
      "to": [
        "visualisation.pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model_species_labels"
      ],
      "from": "pharmacology_sbml_koschorreck2008_insulinclearance_biomd0000000345_model.species_labels"
    }
  ],
  "package": "koschorreck2008-insulin-clearance",
  "runtime": {
    "duration": 24,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This model is from the article: Mathematical modeling and analysis of insulin clearance in vivo. It can be used to explore dose-response dynamics and compare treatment scenarios across conditions.",
  "schema_version": "2.0"
}