Ledzewicz2013 - On optimal chemotherapy with a strongly targeted agent for a model of tumor immune system interactions with generalized logistic growth Lab
About lab
One published Lab
Build with this Lab. Run it anywhere.
Use the same immutable release locally or through managed cloud execution, with its exact version and provenance preserved.
Preparing exact examples…
On optimal chemotherapy with a strongly targeted agent for a model of tumor-immune system interactions with generalized logistic growth.Ledzewicz U1, Olumoye O, Schättler H.1Dept. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_unresolved_tumor_observable_1",
"label": "Initial Unresolved Tumor Observable 1",
"units": "native source value",
"default": 0.1,
"maps_to": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.initial_unresolved_tumor_observable_1",
"description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `y`."
},
{
"name": "initial_unresolved_tumor_observable_2",
"label": "Initial Unresolved Tumor Observable 2",
"units": "native source value",
"default": 600,
"maps_to": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.initial_unresolved_tumor_observable_2",
"description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `x`."
},
{
"name": "a_constant_rate_of_influx_of_t_cells_generated_through_the_primary_organs_rate",
"label": "A Constant Rate Of Influx Of T Cells Generated Through The Primary Organs Rate",
"units": "native source value",
"default": 0.1181,
"maps_to": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.a_constant_rate_of_influx_of_t_cells_generated_through_the_primary_organs_rate",
"description": "A Constant Rate Of Influx Of T Cells Generated Through The Primary Organs Rate. Sets bundled SBML parameter `alpha`."
},
{
"name": "natural_death_of_t_cells_rate",
"label": "Natural Death Of T Cells Rate",
"units": "native source value",
"default": 0.37451,
"maps_to": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.natural_death_of_t_cells_rate",
"description": "Natural Death Of T Cells Rate. Sets bundled SBML parameter `delta`."
}
],
"outputs": [
{
"name": "unresolved_tumor_observable_1",
"maps_to": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.unresolved_tumor_observable_1"
},
{
"name": "unresolved_tumor_observable_2",
"maps_to": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.unresolved_tumor_observable_2"
},
{
"name": "state",
"maps_to": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.species_labels"
}
]
},
"title": "Ledzewicz2013 - On optimal chemotherapy with a strongly targeted agent for a model of tumor immune system interactions with generalized logistic growth Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model_state"
],
"from": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.state"
},
{
"to": [
"visualisation.immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model_summary"
],
"from": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model_species_labels"
],
"from": "immunology_sbml_ledzewicz2013_on_optimal_chemotherapy_with_a_str_biomd0000000919_model.species_labels"
}
],
"package": "ledzewicz2013-on-optimal-chemotherapy-with-a-strongly-targeted",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "On optimal chemotherapy with a strongly targeted agent for a model of tumor-immune system interactions with generalized logistic growth.Ledzewicz U1, Olumoye O, Schättler H.1Dept. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageledzewicz2013-on-optimal-chemotherapy-with-a-strongly-targeted
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother