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The paper describes a model of immunity to melanoma. Created by COPASI 4.25 (Build 207) This model is described in the article: Modeling anti-tumor Th1 and Th2 immunity in the rejection of melanoma Ra.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_melanoma_cells",
"label": "Melanoma Cells",
"units": "native SBML value",
"default": 100000,
"maps_to": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.initial_melanoma_cells",
"description": "Initial Melanoma Cells. Sets the initial value of bundled SBML symbol `T`."
},
{
"name": "initial_helper_t_cells",
"label": "Helper T Cells",
"units": "native SBML value",
"default": 0,
"maps_to": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.initial_helper_t_cells",
"description": "Initial Helper T Cells. Sets the initial value of bundled SBML symbol `Th`."
}
],
"outputs": [
{
"name": "melanoma_cells",
"maps_to": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.melanoma_cells",
"description": "Melanoma Cells observable. Maps to SBML symbol `T`."
},
{
"name": "helper_t_cells",
"maps_to": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.helper_t_cells",
"description": "Helper T Cells observable. Maps to SBML symbol `Th`."
},
{
"name": "state",
"maps_to": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"faithful",
"oncology",
"physiology",
"sbml",
"systemsbiology",
"tumor-growth"
],
"title": "Eftimie2010 - immunity to melanoma Lab",
"models": [
{
"path": "models/core",
"alias": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model_state"
],
"from": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.state"
},
{
"to": [
"visualisation.oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model_summary"
],
"from": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model_species_labels"
],
"from": "oncology_sbml_eftimie2010_immunity_to_melanoma_biomd0000000768_model.species_labels"
}
],
"package": "eftimie2010-immunity-to-melanoma",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "The paper describes a model of immunity to melanoma. Created by COPASI 4.25 (Build 207) This model is described in the article: Modeling anti-tumor Th1 and Th2 immunity in the rejection of melanoma Ra.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageeftimie2010-immunity-to-melanoma
Created2026-05-16
Updated2026-06-13
biomodels_ebicuratedfaithfuloncologyphysiologysbmlsystemsbiologytumor-growthvisualisationother