Costa2015 - Central metabolism of E. coli, extended regulated linlog model ( with additional allosteric regulations than the Model1) Lab
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Metabolism Costa2015Central Metabolism Of EColi Extended Model1504080006Model models core biological dynamics as a OTHER simulation curated from biomodels_ebi (biomodels_ebi:MODEL1504080006), focused on metabol. When you run it, you can track state over time and compare response patterns across parameter settings.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_phosphoenol_pyruvate",
"units": "native SBML value",
"default": 2.67,
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.initial_phosphoenol_pyruvate",
"description": "Initial condition for phosphoenol pyruvate. Maps to bundled SBML symbol `cpep`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
},
{
"name": "initial_extracellular_glucose",
"units": "native SBML value",
"default": 0.0556,
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.initial_extracellular_glucose",
"description": "Initial condition for extracellular glucose. Maps to bundled SBML symbol `cglcex`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
},
{
"name": "initial_glucose_6_phosphate",
"units": "native SBML value",
"default": 3.48,
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.initial_glucose_6_phosphate",
"description": "Initial condition for glucose 6 phosphate. Maps to bundled SBML symbol `cg6p`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
},
{
"name": "initial_microbial_metabolism_state_4",
"units": "native SBML value",
"default": 2.67,
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.initial_microbial_metabolism_state_4",
"description": "Initial condition for microbial metabolism state 4. Maps to bundled SBML symbol `cpyr`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
},
{
"name": "initial_fructose_6_phosphate",
"units": "native SBML value",
"default": 0.6,
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.initial_fructose_6_phosphate",
"description": "Initial condition for fructose 6 phosphate. Maps to bundled SBML symbol `cf6p`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
}
],
"outputs": [
{
"name": "phosphoenol_pyruvate",
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.phosphoenol_pyruvate"
},
{
"name": "extracellular_glucose",
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.extracellular_glucose"
},
{
"name": "glucose_6_phosphate",
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.glucose_6_phosphate"
},
{
"name": "microbial_metabolism_state_4",
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.microbial_metabolism_state_4"
},
{
"name": "fructose_6_phosphate",
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.fructose_6_phosphate"
},
{
"name": "observable_values",
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.observable_values"
},
{
"name": "run_summary",
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.run_summary"
},
{
"name": "observable_labels",
"maps_to": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.observable_labels"
}
]
},
"title": "Costa2015 - Central metabolism of E. coli, extended regulated linlog model ( with additional allosteric regulations than the Model1) Lab",
"models": [
{
"path": "models/core",
"alias": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model",
"parameters": {
"model_path": "data/MODEL1504080006.xml",
"integration_step": 0.1
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model_observable_values"
],
"from": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.observable_values"
},
{
"to": [
"visualisation.metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model_run_summary"
],
"from": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.run_summary"
},
{
"to": [
"visualisation.metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model_observable_labels"
],
"from": "metabolism_sbml_costa2015_central_metabolism_of_e_coli_extended_model1504080006_model.observable_labels"
}
],
"package": "costa2015-central-metabolism-of-e-coli-extended-regulat-02d4c2cf",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Metabolism Costa2015Central Metabolism Of EColi Extended Model1504080006Model models core biological dynamics as a OTHER simulation curated from biomodels_ebi (biomodels_ebi:MODEL1504080006), focused on metabol. When you run it, you can track state over time and compare response patterns across parameter settings.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagecosta2015-central-metabolism-of-e-coli-extended-regulat-02d4c2cf
Created2026-05-15
Updated2026-06-13
biomodels_ebifaithfulmetabolismodesbmltelluriumvisualisationother