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This model is from the article: Interlinked mutual inhibitory positive feedbacks induce robust cellular memory effects. Kim TH, Jung SH, Cho KH FEBS Lett.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_p2_prime",
"label": "Initial P2 Prime",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.initial_p2_prime",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `P2_prime`."
},
{
"name": "initial_model_state_p2",
"label": "Initial Model State P2",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.initial_model_state_p2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `P2`."
},
{
"name": "initial_model_state_r2",
"label": "Initial Model State R2",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.initial_model_state_r2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `R2`."
},
{
"name": "initial_p4_prime",
"label": "Initial P4 Prime",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.initial_p4_prime",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `P4_prime`."
},
{
"name": "initial_p3_prime",
"label": "Initial P3 Prime",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.initial_p3_prime",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `P3_prime`."
},
{
"name": "initial_p1_prime",
"label": "Initial P1 Prime",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.initial_p1_prime",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `P1_prime`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.species_labels"
},
{
"name": "p2_prime",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.p2_prime"
},
{
"name": "model_state_p2",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.model_state_p2"
},
{
"name": "model_state_r2",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.model_state_r2"
},
{
"name": "p4_prime",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.p4_prime"
},
{
"name": "p3_prime",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.p3_prime"
},
{
"name": "p1_prime",
"maps_to": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.p1_prime"
}
]
},
"tags": [
"immunology",
"pharmacology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Kim2007 Cellularmemory Symmetricmodel Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model_state"
],
"from": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model_summary"
],
"from": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model_species_labels"
],
"from": "systemsbiology_sbml_kim2007_cellularmemory_symmetricmodel_biomd0000000180_model.species_labels"
}
],
"package": "kim2007-cellularmemory-symmetricmodel",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "This model is from the article: Interlinked mutual inhibitory positive feedbacks induce robust cellular memory effects. Kim TH, Jung SH, Cho KH FEBS Lett.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagekim2007-cellularmemory-symmetricmodel
Created2026-05-17
Updated2026-06-13
immunologypharmacologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother