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Single-model lab wrapper for Ibrahim2008 - Mitotic Spindle Assembly Checkpoint - Dissociation variant. Ibrahim2008 - Mitotic Spindle Assembly Checkpoint - Dissociation variant The Mitotic Spindle Assembly Checkpoint ((M)SAC) is an evolutionary conserved mechanism. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.
Manifest
{
"io": {
"inputs": [],
"outputs": [
{
"name": "mad1_c_mad2",
"label": "Mad1:C Mad2",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.mad1_c_mad2",
"description": "Tracks Mad1:C Mad2 in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.mad1_c_mad2`."
},
{
"name": "o_mad2",
"label": "O Mad2",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.o_mad2",
"description": "Tracks O Mad2 in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.o_mad2`."
},
{
"name": "mad1_c_mad2_o_mad2",
"label": "Mad1:C Mad2:O Mad2*",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.mad1_c_mad2_o_mad2",
"description": "Tracks Mad1:C Mad2:O Mad2* in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.mad1_c_mad2_o_mad2`."
},
{
"name": "cdc20_apc_c_activator",
"label": "Cdc20 APC/C activator",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.cdc20_apc_c_activator",
"description": "Tracks Cdc20 APC/C activator in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.cdc20_apc_c_activator`."
},
{
"name": "cdc20_c_mad2",
"label": "Cdc20:C Mad2",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.cdc20_c_mad2",
"description": "Tracks Cdc20:C Mad2 in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.cdc20_c_mad2`."
},
{
"name": "bub3_bub_model_state_r1",
"label": "Bub3:Bub Model state R1",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.bub3_bub_model_state_r1",
"description": "Tracks Bub3:Bub Model state R1 in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.bub3_bub_model_state_r1`."
},
{
"name": "mitotic_checkpoint_complex",
"label": "Mitotic checkpoint complex",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.mitotic_checkpoint_complex",
"description": "Tracks Mitotic checkpoint complex in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.mitotic_checkpoint_complex`."
},
{
"name": "bub3_bub_r1_cdc20",
"label": "Bub3:Bub R1:Cdc20",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.bub3_bub_r1_cdc20",
"description": "Tracks Bub3:Bub R1:Cdc20 in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.bub3_bub_r1_cdc20`."
},
{
"name": "apc_c_c",
"label": "APC/C/C",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.apc_c_c",
"description": "Tracks APC/C/C in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.apc_c_c`."
},
{
"name": "mcc_apc_c_c",
"label": "MCC:APC/C/C",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.mcc_apc_c_c",
"description": "Tracks MCC:APC/C/C in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.mcc_apc_c_c`."
},
{
"name": "apc_c_c_cdc20",
"label": "APC/C/C:Cdc20",
"maps_to": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.apc_c_c_cdc20",
"description": "Tracks APC/C/C:Cdc20 in the lab model via `cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.apc_c_c_cdc20`."
}
]
},
"title": "Ibrahim2008 - Mitotic Spindle Assembly Checkpoint - Dissociation variant Lab",
"models": [
{
"path": "models/core",
"alias": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model_state"
],
"from": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.state"
},
{
"to": [
"visualisation.cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model_summary"
],
"from": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.summary"
},
{
"to": [
"visualisation.cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model_species_labels"
],
"from": "cellcycle_sbml_ibrahim2008_mitotic_spindle_assembly_checkpoint_biomd0000000186_model.species_labels"
}
],
"package": "ibrahim2008-spindle-checkpoint-dissociation",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Single-model lab wrapper for Ibrahim2008 - Mitotic Spindle Assembly Checkpoint - Dissociation variant. Ibrahim2008 - Mitotic Spindle Assembly Checkpoint - Dissociation variant The Mitotic Spindle Assembly Checkpoint ((M)SAC) is an evolutionary conserved mechanism. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageibrahim2008-spindle-checkpoint-dissociation
Created2026-05-15
Updated2026-06-13
cellcyclesbmlbiomodels_ebifaithfulvisualisationother