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Kilian2024 - Immune cell dynamics in Cue-Induced Extended Human Colitis ModelSingle-cell technologies such as scRNA-seq and flow cytometry provide critical insights into immune cell behavior in inflam. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_cell",
"label": "Initial Cell",
"units": "native source value",
"default": 0.0468867574754616,
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.initial_cell",
"description": "Initial Cell. Sets the initial value of bundled SBML species `Bcell`."
},
{
"name": "initial_unresolved_immune_observable_1",
"label": "Initial Unresolved Immune Observable 1",
"units": "native source value",
"default": 0.0215256076306623,
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.initial_unresolved_immune_observable_1",
"description": "Initial Unresolved Immune Observable 1. Sets the initial value of bundled SBML species `Tcell`."
},
{
"name": "initial_unresolved_immune_observable_2",
"label": "Initial Unresolved Immune Observable 2",
"units": "native source value",
"default": 0.0608414487144472,
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.initial_unresolved_immune_observable_2",
"description": "Initial Unresolved Immune Observable 2. Sets the initial value of bundled SBML species `Mac`."
},
{
"name": "initial_neutr",
"label": "Initial Neutr",
"units": "native source value",
"default": 0.0481656099063014,
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.initial_neutr",
"description": "Initial Neutr. Sets the initial value of bundled SBML species `Neutr`."
},
{
"name": "initial_unresolved_immune_observable_3",
"label": "Initial Unresolved Immune Observable 3",
"units": "native source value",
"default": 0.300977731108012,
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.initial_unresolved_immune_observable_3",
"description": "Initial Unresolved Immune Observable 3. Sets the initial value of bundled SBML species `Epi`."
}
],
"outputs": [
{
"name": "cell",
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.cell"
},
{
"name": "unresolved_immune_observable_1",
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.unresolved_immune_observable_1"
},
{
"name": "unresolved_immune_observable_2",
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.unresolved_immune_observable_2"
},
{
"name": "neutr",
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.neutr"
},
{
"name": "unresolved_immune_observable_3",
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.unresolved_immune_observable_3"
},
{
"name": "state",
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.species_labels"
}
]
},
"title": "Kilian2024 - Immune cell dynamics in Cue-Induced Extended Human Colitis Model Lab",
"models": [
{
"path": "models/core",
"alias": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model_state"
],
"from": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.state"
},
{
"to": [
"visualisation.immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model_summary"
],
"from": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model_species_labels"
],
"from": "immunology_sbml_kilian2024_immune_cell_dynamics_in_cue_induced_e_model2502180001_model.species_labels"
}
],
"package": "kilian2024-immune-cell-dynamics-in-cue-induced-extended",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Kilian2024 - Immune cell dynamics in Cue-Induced Extended Human Colitis ModelSingle-cell technologies such as scRNA-seq and flow cytometry provide critical insights into immune cell behavior in inflam. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagekilian2024-immune-cell-dynamics-in-cue-induced-extended
Created2026-05-15
Updated2026-06-13
immunologysbmlbiomodels_ebifaithfulcuratedvisualisationother