Kollarovic2016 - Cell fate decision at G1-S transition Lab

{
  "io": {
    "inputs": [
      {
        "name": "ddr",
        "label": "DDR",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.ddr",
        "description": "Controls DDR in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.ddr`."
      },
      {
        "name": "dna_damagefoci_0",
        "label": "DNA damagefoci 0",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.dna_damagefoci_0",
        "description": "Controls DNA damagefoci 0 in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.dna_damagefoci_0`."
      },
      {
        "name": "base_dna_damage",
        "label": "Base DNA damage",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.base_dna_damage",
        "description": "Controls Base DNA damage in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.base_dna_damage`."
      }
    ],
    "outputs": [
      {
        "name": "cyclin_e",
        "label": "Cyclin E",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.cyclin_e",
        "description": "Tracks Cyclin E in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.cyclin_e`."
      },
      {
        "name": "cdk2",
        "label": "CDK2",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.cdk2",
        "description": "Tracks CDK2 in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.cdk2`."
      },
      {
        "name": "cyclin_ecdk2",
        "label": "Cyclin ECdk2",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.cyclin_ecdk2",
        "description": "Tracks Cyclin ECdk2 in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.cyclin_ecdk2`."
      },
      {
        "name": "cyclin_ecdk2a",
        "label": "Cyclin ECdk2a",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.cyclin_ecdk2a",
        "description": "Tracks Cyclin ECdk2a in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.cyclin_ecdk2a`."
      },
      {
        "name": "p21",
        "label": "P21",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.p21",
        "description": "Tracks P21 in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.p21`."
      },
      {
        "name": "dna_damage_model_state_c",
        "label": "DNA damage Model state C",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.dna_damage_model_state_c",
        "description": "Tracks DNA damage Model state C in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.dna_damage_model_state_c`."
      },
      {
        "name": "dna_damage_s",
        "label": "DNA damage S",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.dna_damage_s",
        "description": "Tracks DNA damage S in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.dna_damage_s`."
      },
      {
        "name": "p53_tumor_suppressor",
        "label": "p53 tumor suppressor",
        "maps_to": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.p53_tumor_suppressor",
        "description": "Tracks p53 tumor suppressor in the lab model via `cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.p53_tumor_suppressor`."
      }
    ]
  },
  "title": "Kollarovic2016 - Cell fate decision at G1-S transition Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model_state"
      ],
      "from": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.state"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model_summary"
      ],
      "from": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.summary"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model_species_labels"
      ],
      "from": "cellcycle_sbml_kollarovic2016_cell_fate_decision_at_g1_s_transi_biomd0000000632_model.species_labels"
    }
  ],
  "package": "kollarovic2016-g1-s-cell-fate",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Single-model lab wrapper for Kollarovic2016 - Cell fate decision at G1-S transition. Kollarovic2016 - Cell fate decision at G1-Stransition This model is described in the article: To senesce or not to senesce: how primary human fibroblasts decide their cell fate after DNA damage. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.",
  "schema_version": "2.0"
}