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Mathematical model of blood coagulation that simulates the effect of coated platelets on thrombin generation. It can be used to explore systemsbiology susree2018 effect of coated platelets dynamics and compare simulation behavior across conditions.
Manifest
{
"io": {
"inputs": [
{
"name": "initial_a1_at",
"label": "Initial A1 At",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.initial_a1_at",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `a1AT`."
},
{
"name": "initial_ii_m",
"label": "Initial Ii M",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.initial_ii_m",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `II_m`."
},
{
"name": "initial_model_state_x_m",
"label": "Initial Model State X M",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.initial_model_state_x_m",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `X_m`."
},
{
"name": "initial_va_m",
"label": "Initial Va M",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.initial_va_m",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Va_m`."
},
{
"name": "initial_i_xa_m",
"label": "Initial I Xa M",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.initial_i_xa_m",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `IXa_m`."
},
{
"name": "initial_vii_ia_m",
"label": "Initial Vii Ia M",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.initial_vii_ia_m",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `VIIIa_m`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.species_labels"
},
{
"name": "a1_at",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.a1_at"
},
{
"name": "ii_m",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.ii_m"
},
{
"name": "x_m",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.x_m"
},
{
"name": "va_m",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.va_m"
},
{
"name": "i_xa_m",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.i_xa_m"
},
{
"name": "vii_ia_m",
"maps_to": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.vii_ia_m"
}
]
},
"tags": [
"generegulation",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Susree2018 Effect Of Coated Platelets On Thrombin Generation Lab",
"models": [
{
"path": "models/core",
"alias": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model_state"
],
"from": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model_summary"
],
"from": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model_species_labels"
],
"from": "systemsbiology_sbml_susree2018_effect_of_coated_platelets_on_thrombi_model1808080001_model.species_labels"
}
],
"package": "susree2018-effect-of-coated-platelets-on-thrombin-generation",
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"version": "1.0.0",
"description": "Mathematical model of blood coagulation that simulates the effect of coated platelets on thrombin generation. It can be used to explore systemsbiology susree2018 effect of coated platelets dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
}Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagesusree2018-effect-of-coated-platelets-on-thrombin-generation
Created2026-05-17
Updated2026-06-13
generegulationsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisationother