Mechanotransduction & Inflammation Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_source_defined_calcium_state",
        "label": "Initial source-defined CA2+ state",
        "maps_to": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.initial_source_defined_calcium_state",
        "description": "Initial level of source-defined CA2+ state. Maps to SBML symbol `s423`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_source_defined_calcium_state_2",
        "label": "Initial source-defined CA2+ state",
        "maps_to": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.initial_source_defined_calcium_state_2",
        "description": "Initial level of source-defined CA2+ state. Maps to SBML symbol `s425`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_camp",
        "label": "Initial cAMP",
        "maps_to": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.initial_camp",
        "description": "Initial level of cAMP. Maps to SBML symbol `s859`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "source_defined_nfkb1_state",
        "label": "source-defined NFKB1 state",
        "maps_to": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.source_defined_nfkb1_state",
        "description": "source-defined NFKB1 state. Maps to SBML symbol `s15` and is emitted in native SBML units."
      },
      {
        "name": "source_defined_akt1_state",
        "label": "source-defined AKT1 state",
        "maps_to": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.source_defined_akt1_state",
        "description": "source-defined AKT1 state. Maps to SBML symbol `s866` and is emitted in native SBML units."
      },
      {
        "name": "arp2_3_complex",
        "label": "ARP2 3 Complex",
        "maps_to": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.arp2_3_complex",
        "description": "ARP2 3 Complex. Maps to SBML symbol `s907` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "immune-signaling"
  ],
  "title": "Mechanotransduction & Inflammation Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model_state"
      ],
      "from": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model_summary"
      ],
      "from": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model_species_labels"
      ],
      "from": "signaling_sbml_mechanotransduction_and_inflammation_model2406110001_model.species_labels"
    }
  ],
  "package": "nardini2015-mechanotransduction-and-inflammation",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for immune signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}